Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 15/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.40 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2744306 | 0.88 | TLR7 (0.83) | TLR7TLR8 | |
| SCHEMBL12409397 | 0.81 | TLR7 (0.81) | TLR7TDP1TLR8PIM3PIM1 | |
| SCHEMBL2743937 | 0.80 | TLR7 (0.80) | TLR7TLR8 | |
| Cpg-52852 SCHEMBL29371102 | 0.79 | TLR7 (1.00) | TLR7TLR8 | |
| Cpg-52852 SCHEMBL483385 | 0.79 | TLR7 (1.00) | TLR7TLR8 | |
| SCHEMBL2114514 | 0.79 | TLR7 (0.68) | TLR7TLR8 | |
| SCHEMBL483689 | 0.77 | TLR7 (0.85) | TLR7TLR8 | |
| SCHEMBL29852269 | 0.77 | TLR7 (0.85) | TLR7TLR8 | |
| SCHEMBL3884418 | 0.77 | TLR7 (0.72) | TLR7TDP1TLR8 | |
| SCHEMBL728467 | 0.77 | TLR7 (0.84) | TLR7TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1851224-A2 | HYDROXYALKYL SUBSTITUTED IMIDAZOQUINOLINES | 3M Innovative Properties Company (US) | 2007-11-07 | — | — | EP | disclosed |
| WO-2006098852-A2 | HYDROXYALKYL SUBSTITUTED IMIDAZOQUINOLINES | COLEY PHARMACEUTICAL GROUP, INC. (US) | 2006-09-21 | — | — | WO | disclosed |