Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 4/20 | 0.36 |
| ▸ | P2RX2 | Q9UBL9 | 4/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | TTK | P33981 | 1/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.35 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL456396 | 0.85 | TLR8 (0.57) | TLR8GAAALDH1A1P2RX3P2RX2 | |
| SCHEMBL4864975 | 0.85 | MAPT (0.44) | TLR8GAAALDH1A1CYP3A4TDP1 | |
| SCHEMBL33961 | 0.85 | MAPT (0.44) | TLR8GAAALDH1A1CYP3A4TDP1 | |
| Hydrochloric Acid SCHEMBL10775821 | 0.83 | TLR8 (0.55) | TLR8GAAALDH1A1P2RX3P2RX2 | |
| Hydrochloric Acid SCHEMBL970834 | 0.83 | MAPT (0.42) | TLR8GAAALDH1A1CYP3A4TDP1 | |
| Hydrochloric Acid SCHEMBL2479718 | 0.83 | MAPT (0.42) | TLR8GAAALDH1A1CYP3A4TDP1 | |
| SCHEMBL23620104 | 0.72 | PIK3CA (0.40) | ALDH1A1CYP3A4TDP1POLBTSHR | |
| SCHEMBL11993969 | 0.72 | PIK3CA (0.41) | GAAALDH1A1CYP3A4TDP1POLB | |
| SCHEMBL20856210 | 0.71 | MAPT (0.38) | GAATDP1MAPTCASP1NPC1 | |
| SCHEMBL22437180 | 0.71 | MAPT (0.38) | ALDH1A1CYP3A4TDP1POLBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1846361-A2 | 3-AMINO-2-AMINOMETHYLPHENOL DERIVATIVES AND COLORANTS COMPRISING THESE COMPOUNDS | Wella Aktiengesellschaft (DE) | 2007-10-24 | — | — | EP | disclosed |
| WO-2006086374-A2 | 3-AMINO-2-AMINOMETHYLPHENOL DERIVATIVES AND COLORANTS COMPRISING THESE COMPOUNDS | THE PROCTER & GAMBLE COMPANY (US) | 2006-08-17 | — | — | WO | disclosed |