Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA known ✓ | P42336 | 1/20 | 0.38 |
| ▸ | GAA known ✓ | P10253 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | TTK | P33981 | 1/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.41 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2479718 | 1.00 | MAPT (0.42) | MAPTCASP1AURKATTKAURKB | |
| SCHEMBL4864975 | 0.97 | MAPT (0.44) | MAPTCASP1AURKATTKAURKB | |
| SCHEMBL33961 | 0.97 | MAPT (0.44) | MAPTCASP1AURKATTKAURKB | |
| Hydrochloric Acid SCHEMBL9212548 | 0.84 | ALDH1A1 (0.42) | MAPTCASP1AURKATTKAURKB | |
| SCHEMBL23620104 | 0.83 | PIK3CA (0.40) | MAPTCASP1AURKATTKAURKB | |
| SCHEMBL11993969 | 0.83 | PIK3CA (0.41) | MAPTCASP1AURKATTKAURKB | |
| SCHEMBL5340076 | 0.83 | TLR8 (0.46) | MAPTCASP1AURKATTKAURKB | |
| SCHEMBL11996546 | 0.81 | MAPT (0.38) | MAPTCASP1AURKATTKAURKB | |
| SCHEMBL22437180 | 0.81 | MAPT (0.38) | MAPTCASP1AURKATTKAURKB | |
| SCHEMBL20856210 | 0.81 | MAPT (0.38) | MAPTCASP1AURKATTKAURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115980205-B | Quantitative and/or qualitative method for simultaneously measuring 54 hair dyes in hair dye product | 江苏省食品药品监督检验研究院 | 2025-04-22 | — | — | CN | claimed |
| CN-119310203-A | Method for detecting hair dye component in hair dye product | 上海净畅检测科技有限公司 | 2025-01-14 | — | — | CN | claimed |
| CN-115980205-A | Quantitative and/or qualitative method for simultaneously measuring 54 hair dyes in hair dyeing product | 江苏省食品药品监督检验研究院 | 2023-04-18 | — | — | CN | claimed |
| CN-105753832-A | Preparation method of 4-(2-hydroxyl ethylamino)-1,2-methylenedioxyphenyl hydrochloride | 宜兴市新宇化工有限公司 | 2016-07-13 | — | — | CN | claimed |
| US-20110020251-A1 | Ultraviolet-Absorbing Compounds | AVOCA LLC | 2011-01-27 | — | — | US | claimed |
| CN-115980205-B | Quantitative and/or qualitative method for simultaneously measuring 54 hair dyes in hair dye product | 江苏省食品药品监督检验研究院 | 2025-04-22 | — | — | CN | disclosed |
| CN-119310203-A | Method for detecting hair dye component in hair dye product | 上海净畅检测科技有限公司 | 2025-01-14 | — | — | CN | disclosed |
| CN-119310203-A | Method for detecting hair dye component in hair dye product | 上海净畅检测科技有限公司 | 2025-01-14 | — | — | CN | disclosed |
| CN-115980205-A | Quantitative and/or qualitative method for simultaneously measuring 54 hair dyes in hair dyeing product | 江苏省食品药品监督检验研究院 | 2023-04-18 | — | — | CN | disclosed |
| CN-107693382-A | Percarbonic acid sodium form powder hair dye and preparation method thereof | 雅达（厦门）日化有限公司 | 2018-02-16 | — | — | CN | disclosed |
| CN-105753832-A | Preparation method of 4-(2-hydroxyl ethylamino)-1,2-methylenedioxyphenyl hydrochloride | 宜兴市新宇化工有限公司 | 2016-07-13 | — | — | CN | disclosed |
| CN-105753832-A | Preparation method of 4-(2-hydroxyl ethylamino)-1,2-methylenedioxyphenyl hydrochloride | 宜兴市新宇化工有限公司 | 2016-07-13 | — | — | CN | disclosed |
| WO-2003060015-A1 | YELLOW CATIONIC DYES FOR DYING OF ORGANIC MATERIAL | CIBA SPECIALITY CHEMICALS HOLDING INC. (CH) | 2003-07-24 | — | — | WO | disclosed |
| WO-2003032939-A1 | METHOD OF COLOURING KERATIN-CONTAINING FIBRES USING DIAZONIUM SALTS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2003-04-24 | — | — | WO | disclosed |
| WO-2003029359-A1 | CATIONIC REACTIVE DYES | CIBA SPECIALTY CHEMICALS HOLDINGS INC. (CH) | 2003-04-10 | — | — | WO | disclosed |
| EP-1203141-A1 | LINKAGE OF AGENTS TO TISSUE | Pericor Science, Inc. (US) | 2002-05-08 | — | — | EP | disclosed |
| WO-2001006829-A2 | LINKAGE OF AGENTS TO TISSUE | PERICOR SCIENCE, INC. (US) | 2001-02-01 | — | — | WO | disclosed |
| EP-0750490-B1 | ISATIN DERIVATIVES FOR DYEING KERATIN-CONTAINING FIBRES | HENKEL KGAA (DE) | 2000-11-08 | — | — | EP | disclosed |
| US-5743919-A | HAIR DYES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1998-04-28 | — | — | US | disclosed |
| WO-1995011002-A1 | ETHANE DIONES FOR USE IN DYEING KERATIN-CONTAINING FIBRES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1995-04-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110020251-A1 | Ultraviolet-Absorbing Compounds | UFM1, UHRF1, CUTA | PIK3CA 3333/4885GAA 4597/4885MAPT 322/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.