Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5077321 | 0.81 | NUDT1 (0.30) | — | |
| SCHEMBL5081649 | 0.78 | — | — | |
| SCHEMBL5084704 | 0.75 | — | — | |
| SCHEMBL5081562 | 0.74 | — | — | |
| SCHEMBL14746711 | 0.72 | — | — | |
| SCHEMBL13864370 | 0.71 | — | — | |
| SCHEMBL5077690 | 0.70 | — | — | |
| SCHEMBL6874254 | 0.70 | CES1 (0.32) | — | |
| SCHEMBL1567062 | 0.69 | TSHR (0.32) | — | |
| SCHEMBL5085457 | 0.69 | SLC6A2 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2413941-A1 | RENIN INHIBITORS | Merck Sharp & Dohme Corp. (US) | 2012-02-08 | — | — | EP | disclosed |
| WO-2010114978-A1 | RENIN INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2010-10-07 | — | — | WO | disclosed |