SCHEMBL534023

SCHEMBL534023

COC(=O)[C@@H](C)Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL882421 1.00
SCHEMBL37355 1.00
SCHEMBL29615322 1.00
SCHEMBL11142521 0.97
SCHEMBL7717304 0.89 SMN1; SMN2 (0.41)
SCHEMBL31468683 0.82 SMN1; SMN2 (0.39)
SCHEMBL1332029 0.78
SCHEMBL5424391 0.78 TSHR (0.38)
SCHEMBL2864267 0.78 SMN1; SMN2 (0.48)
SCHEMBL952090 0.78 TSHR (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118908877-A Free radical polymerization photocatalyst based on diphenylcarbazole, preparation method and photocuring application thereof 西安交通大学 2024-11-08 CN claimed
EP-4704830-A2 MRGPRX2 INHIBITORS AND METHODS OF USE THEREOF Septerna, Inc. (US) 2026-03-11 EP disclosed
US-12404241-B2 Substituted 3-((3-aminophenyl)amino)piperidine-2,6-dione compounds, compositions thereof, and methods of treatment therewith CELGENE CORPORATION (US) 2025-09-02 US disclosed
US-20250263408-A1 SPLEEN TYROSINE KINASE INHIBITORS UNIQUEST PTY LTD (AU) 2025-08-21 US disclosed
US-20250213555-A1 SUBSTITUTED TETRAHYDROFURAN ANALOGS AS MODULATORS OF SODIUM CHANNELS VERTEX PHARMACEUTICALS INCORPORATED (US) 2025-07-03 US disclosed
US-12310975-B2 Modulators of BCL6 proteolysis and associated methods of use ARVINAS OPERATIONS, INC. (US) 2025-05-27 US disclosed
EP-4504724-A1 SPLEEN TYROSINE KINASE INHIBITORS Uniquest Pty Limited (AU) 2025-02-12 EP disclosed
CN-119325474-A Spleen tyrosine kinase inhibitors 尤尼奎斯特公司 2025-01-17 CN disclosed
CN-119219606-A Substituted 3- ((3-aminophenyl) amino) piperidine-2, 6-dione compounds, compositions thereof, and methods of treatment using the same 细胞基因公司 2024-12-31 CN disclosed
CN-119019369-A Bifunctional molecules comprising an E3 ubiquitin ligase binding moiety linked to a BCL6 targeting moiety 阿尔维纳斯运营股份有限公司 2024-11-26 CN disclosed
CN-1195759-C Process for preparing benzoxazine derivatives and intermediates thereof DAIICHI SEIYAKU CO (JP) 2005-04-06 CN disclosed
CN-1532181-A Intermediate for preparing benzoxazine derivative and preparation method thereof 第一制药株式会社 2004-09-29 CN disclosed
CN-1379779-A Process for preparing benzoxazine derivatives and intermediates thereof DAIICHI SEIYAKU CO (JP) 2002-11-13 CN disclosed
US-6379552-B1 LIQUID PHASE; USING CYCLODEXTRIN TORAY INDUSTRIES, INC. (JP) 2002-04-30 US disclosed
EP-0970936-A1 A method for resolving optical isomers TORAY INDUSTRIES, INC. (JP) 2000-01-12 EP disclosed
EP-0462813-B1 Bicyclic pyran derivatives and their use as inhibitors of 5-lipoxygenase ZENECA LTD (GB) 1995-10-25 EP disclosed
US-5373007-A Lipoxygenase inhibitors ZENECA LIMITED (GB) 1994-12-13 US disclosed
US-5321025-A Inhibitors of 5-lipoxygenase IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1994-06-14 US disclosed
US-5217969-A Antiinflammatory, antiulcer agent IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1993-06-08 US disclosed
EP-0462813-A2 Bicyclic pyran derivatives and their use as inhibitors of 5-lipoxygenase ZENECA LIMITED (GB) 1991-12-27 EP disclosed