SCHEMBL952090

SCHEMBL952090

CC(Cl)C(=O)OC(=O)C(C)Cl

nearest known ligand 0.38

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.38
SMN1; SMN2 Q16637 1/20 0.32
ALDH1A1 P00352 3/20 0.32
LMNA P02545 1/20 0.32
SOAT1 P35610 1/20 0.30
TP53 P04637 1/20 0.30
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4154811 0.88 TSHR (0.35) TSHRALDH1A1SOAT1
SCHEMBL950259 0.87 ALDH1A1 (0.33) TSHRALDH1A1
SCHEMBL953463 0.87 TSHR (0.31) TSHR
SCHEMBL3148591 0.85
SCHEMBL4154813 0.85
SCHEMBL11475673 0.83
SCHEMBL952092 0.81 NAAA (0.37) TSHRALDH1A1LMNASOAT1
SCHEMBL5424391 0.80 TSHR (0.38) TSHRSMN1; SMN2ALDH1A1LMNASOAT1
SCHEMBL951592 0.79 FAAH (0.30)
SCHEMBL493899 0.79 PRKCA (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119505178-B Cured product of organic phosphine modified unsaturated resin and polyhalogenated compound and preparation method thereof 浙江工业大学 2025-04-04 CN claimed
CN-119505178-A Cured product of organic phosphine modified unsaturated resin and polyhalogenated compound and preparation method thereof 浙江工业大学 2025-02-25 CN claimed
CN-118653302-B Preparation method of long-acting antibacterial cellulose material 北京林业大学 2024-11-15 CN claimed
CN-118653302-A Preparation method of long-acting antibacterial cellulose material 北京林业大学 2024-09-17 CN claimed
CN-117624613-A Degradable phosphorus/silicon composite antibacterial/flame-retardant material and preparation method thereof 浙江工业大学 2024-03-01 CN claimed
CN-119505178-B Cured product of organic phosphine modified unsaturated resin and polyhalogenated compound and preparation method thereof 浙江工业大学 2025-04-04 CN disclosed
CN-119505178-A Cured product of organic phosphine modified unsaturated resin and polyhalogenated compound and preparation method thereof 浙江工业大学 2025-02-25 CN disclosed
CN-118653302-B Preparation method of long-acting antibacterial cellulose material 北京林业大学 2024-11-15 CN disclosed
CN-118653302-A Preparation method of long-acting antibacterial cellulose material 北京林业大学 2024-09-17 CN disclosed
CN-117624613-A Degradable phosphorus/silicon composite antibacterial/flame-retardant material and preparation method thereof 浙江工业大学 2024-03-01 CN disclosed
US-20210387990-A1 METHOD FOR PRODUCING DIMETHOXYBENZENE COMPOUND TAIHO PHARMACEUTICAL CO., LTD. (JP) 2021-12-16 US disclosed
US-20210388002-A1 DIMETHOXYBENZENE COMPOUND ANALOGS, METHODS FOR ANALYZING SAID COMPOUNDS AND STANDARD PRODUCTS OF SAID COMPOUNDS TAIHO PHARMACEUTICAL CO., LTD. (JP) 2021-12-16 US disclosed
US-4477443-A INCREASED ANTIBIOTIC ACTIVITY Zaidan Hojin Biselbutsu Kagaku Kenkyu Kai (Microbial Chemistry Research Foundation) (JP) 1984-10-16 US disclosed
EP-0070170-A1 Tylosin derivatives, their preparation and pharmaceutical compositions containing them ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) 1983-01-19 EP disclosed
US-4255594-A Hydrogenation of halogen-containing carboxylic anhydrides ALLIED CHEMICAL CORPORATION (US) 1981-03-10 US disclosed
US-4203898-A ANTICARCINOGENIC ELI LILLY AND COMPANY (US) 1980-05-20 US disclosed
US-4192871-A ANAESTHETICS - STEROIDS GLAXO LABORATORIES LIMITED (GB) 1980-03-11 US disclosed
US-4015995-A CATALYST COMPRISING ACID-RELEASING COMPOUND AND A BASE CHEVRON RESEARCH COMPANY (US) 1977-04-05 US disclosed
US-3958931-A Wool dyeing with epihalohydrin or chloroacetamide quarternized polyglycolamine assisted dye solution CIBA-GEIGY AG (CH) 1976-05-25 US disclosed
US-3943084-A Method for delaying the setting of and acid-settable liquid in a terrestrial zone CHEVRON RESEARCH COMPANY (US) 1976-03-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210387990-A1 METHOD FOR PRODUCING DIMETHOXYBENZENE COMPOUND CYP1B1, PAH, CYP4B1 TSHR 4443/4885SMN1; SMN2 1782/4885ALDH1A1 40/4885
US-20210388002-A1 DIMETHOXYBENZENE COMPOUND ANALOGS, METHODS FOR ANALYZING SAID COMPOUNDS AND STANDARD PRODUCTS OF SAID COMPOUNDS DDC, PAH, DDT TSHR 4454/4885SMN1; SMN2 1818/4885ALDH1A1 12/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.