Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | RAD52 | P43351 | 1/20 | 0.47 |
| ▸ | UBE2N | P61088 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.46 |
| ▸ | GMNN | O75496 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | THPO | P40225 | 1/20 | 0.46 |
| ▸ | MTOR | P42345 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Amicarbalide SCHEMBL1818799 | 0.84 | PLAU (0.65) | PLAUMAPTRAB9AALDH1A1LMNA | |
| SCHEMBL13791589 | 0.79 | PLAU (0.71) | PLAUMAPTRAB9AALDH1A1NPC1 | |
| SCHEMBL27645846 | 0.78 | C1S (0.65) | POLBMAPTKDM4ERAD52UBE2N | |
| SCHEMBL12348392 | 0.77 | MEN1 (0.59) | PLAUPOLBMAPTRAB9AALDH1A1 | |
| Benzamidine SCHEMBL27925636 | 0.77 | POLB (0.61) | POLBMAPTKDM4ERAD52UBE2N | |
| Benzamidine SCHEMBL5522150 | 0.77 | POLB (0.61) | POLBMAPTKDM4ERAD52UBE2N | |
| SCHEMBL12049694 | 0.76 | PLAU (0.55) | PLAURAB9AALDH1A1NPC1HPN | |
| SCHEMBL4226386 | 0.74 | PLAU (0.55) | PLAUALDH1A1HPNF10PRSS1 | |
| SCHEMBL13568446 | 0.73 | MAPT (0.67) | MAPTNPSR1RAB9AALDH1A1LMNA | |
| SCHEMBL2762224 | 0.72 | PLAU (0.55) | PLAUMAPTLMNASMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7241845-B2 | Random block copolymers | OCUTEC LIMITED (GB) | 2007-07-10 | — | — | US | disclosed |
| US-20040198901-A1 | Random block copolymers | BTG INTERNATIONAL LIMITED (GB) | 2004-10-07 | — | — | US | disclosed |
| US-6200600-B1 | Controlled delay release device | BTG INTERNATIONAL LIMITED (GB) | 2001-03-13 | — | — | US | disclosed |
| EP-0572615-B1 | Medicament for the Treatment of Protozoal Infections caused by Babesia | WELLCOME FOUND (GB) | 2000-03-15 | — | — | EP | disclosed |
| EP-0517771-B1 | DISPENSING DEVICE | BTG INT LTD (GB) | 1999-04-14 | — | — | EP | disclosed |
| EP-0878190-A1 | Dispensing device | BTG INTERNATIONAL LIMITED (GB) | 1998-11-18 | — | — | EP | disclosed |
| US-5776981-A | Use of acyl urea compounds for controlling endoparasites and ectoparasites of warm-blooded animals | NOVARTIS CORPORATION (US) | 1998-07-07 | — | — | US | disclosed |
| US-5776982-A | Use of acyl urea compounds for controlling endoparasites and ectoparasites of warm-blooded animals | NOVARTIS CORPORATION (US) | 1998-07-07 | — | — | US | disclosed |
| EP-0691992-B1 | RANDOM BLOCK COPOLYMERS | BRITISH TECH GROUP (GB) | 1998-05-20 | — | — | EP | disclosed |
| EP-0691992-A1 | RANDOM BLOCK COPOLYMERS | BTG INTERNATIONAL LIMITED (GB) | 1996-01-17 | — | — | EP | disclosed |
| WO-1986003941-A1 | USE OF ACYL UREA COMPOUNDS FOR CONTROLLING ENDOPARASITES AND ECTOPARASITES OF WARM-BLOODED ANIMALS | UNION CARBIDE CORPORATION (US) | 1986-07-17 | — | — | WO | disclosed |
| US-4584188-A | POLYETHER OR POLYTHIOETHER COPOLYMERS AS CONTROLLED RELEASE CARRIERS FOR DRUGS | NATIONALE RESEARCH DEVELOPMENT CORPORATION (GB) | 1986-04-22 | — | — | US | disclosed |
| EP-0168401-A1 | IMMUNOGENIC COMPOSITIONS | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1986-01-22 | — | — | EP | disclosed |
| US-4528365-A | Hydrogels | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1985-07-09 | — | — | US | disclosed |
| EP-0132384-A2 | Controlled release device | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1985-01-30 | — | — | EP | disclosed |
| WO-1984003629-A1 | IMMUNOGENIC COMPOSITIONS | CRIGHTON DAVID BARRY | 1984-09-27 | — | — | WO | disclosed |
| US-4438258-A | POLYMERIZED CYCLIC ETHER OR CYCLIC SULFIDE, HYDROPHILIC POLYMER | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1984-03-20 | — | — | US | disclosed |
| EP-0076636-A1 | Sustained release compositions | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1983-04-13 | — | — | EP | disclosed |
| EP-0076158-A2 | Compositions comprising encapsulated particles | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1983-04-06 | — | — | EP | disclosed |
| EP-0067671-A2 | Hydrogels | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1982-12-22 | — | — | EP | disclosed |