Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | RAB9A | P51151 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | PKM | P14618 | 2/20 | 0.61 |
| ▸ | BLM | P54132 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | RECQL | P46063 | 2/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | GMNN | O75496 | 1/20 | 0.61 |
| ▸ | THPO | P40225 | 1/20 | 0.61 |
| ▸ | MTOR | P42345 | 1/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.61 |
| ▸ | F2 | P00734 | 3/20 | 0.57 |
| ▸ | F10 | P00742 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzamidine SCHEMBL5522150 | 1.00 | POLB (0.61) | POLBALDH1A1LMNARAB9ASMN1; SMN2 | |
| Benzamidine SCHEMBL10711784 | 0.82 | F2 (0.76) | POLBLMNAPKMBLMMAPT | |
| Stilbamidine SCHEMBL3934275 | 0.81 | POLB (0.78) | POLBALDH1A1LMNARAB9ASMN1; SMN2 | |
| Stilbamidine SCHEMBL20787646 | 0.81 | POLB (0.78) | POLBALDH1A1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL5522149 | 0.81 | POLB (0.74) | POLBALDH1A1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL27645846 | 0.81 | C1S (0.65) | POLBALDH1A1LMNARAB9ASMN1; SMN2 | |
| Benzamidine SCHEMBL9123469 | 0.81 | F2 (0.73) | POLBLMNAPKMBLMMAPT | |
| Benzamidine SCHEMBL2810507 | 0.79 | F2 (0.70) | POLBPKMBLMMAPTRECQL | |
| Benzamidine SCHEMBL3378018 | 0.79 | F2 (0.70) | POLBPKMBLMMAPTRECQL | |
| Benzamidine SCHEMBL11393583 | 0.79 | F2 (0.70) | POLBLMNAPKMBLMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103421876-A | High throughput screening method for antimicrobial compounds and application of high throughput screening method | UNIV HUAZHONG AGRICULTURAL | 2013-12-04 | — | — | CN | claimed |
| CN-103421876-A | High throughput screening method for antimicrobial compounds and application of high throughput screening method | UNIV HUAZHONG AGRICULTURAL | 2013-12-04 | — | — | CN | disclosed |