Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.75 |
| ▸ | CA12 | O43570 | 1/20 | 0.72 |
| ▸ | CA1 | P00915 | 1/20 | 0.72 |
| ▸ | CA2 | P00918 | 1/20 | 0.72 |
| ▸ | CA7 | P43166 | 1/20 | 0.72 |
| ▸ | CA9 | Q16790 | 1/20 | 0.72 |
| ▸ | GAA | P10253 | 2/20 | 0.71 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.70 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.69 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.67 |
| ▸ | TSHR | P16473 | 2/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.67 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.67 |
| ▸ | KIF11 | P52732 | 1/20 | 0.66 |
| ▸ | PKM | P14618 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19752680 | 0.90 | HSD17B10 (0.77) | HSD17B10CA12CA1CA2CA7 | |
| SCHEMBL1227524 | 0.90 | HSD17B10 (0.77) | HSD17B10CA12CA1CA2CA7 | |
| SCHEMBL10112951 | 0.89 | HSD17B10 (0.76) | HSD17B10CA12CA1CA2CA7 | |
| SCHEMBL28484545 | 0.88 | HSD17B10 (0.70) | HSD17B10CA12CA1CA2CA7 | |
| SCHEMBL24624782 | 0.88 | MAPK1 (0.68) | HSD17B10CA12CA1CA2CA7 | |
| SCHEMBL19752649 | 0.88 | MAPT (0.78) | HSD17B10CA12CA1CA2CA7 | |
| SCHEMBL19752622 | 0.88 | MAPT (0.78) | HSD17B10CA12CA1CA2CA7 | |
| SCHEMBL5340383 | 0.88 | MAPT (0.78) | HSD17B10CA12CA1CA2CA7 | |
| SCHEMBL28490632 | 0.88 | HSD17B10 (0.73) | HSD17B10CA12CA1CA2CA7 | |
| SCHEMBL18025267 | 0.88 | KIF11 (0.75) | HSD17B10CA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025215108-A1 | DUAL G9A/GSK-3ß INHIBITORS | UNIVERSITAT DE BARCELONA (ES) | 2025-10-16 | — | — | WO | claimed |
| WO-2025215108-A1 | DUAL G9A/GSK-3ß INHIBITORS | UNIVERSITAT DE BARCELONA (ES) | 2025-10-16 | — | — | WO | disclosed |
| CN-112812066-B | Synthesis method of dihydropyrimidinone compound | 宜春学院 | 2023-04-25 | — | — | CN | disclosed |
| CN-110437100-B | Preparation method and application of novel ionic salicylaldehyde Schiff base zirconium complex | 山西医科大学 | 2022-03-11 | — | — | CN | disclosed |
| CN-106632071-B | Method for preparing 3, 4-dihydropyrimidine-2-one derivative by promoting high-efficiency catalysis of titanocene dichloride with ethanol | 陕西师范大学 | 2021-07-09 | — | — | CN | disclosed |
| CN-112812066-A | Synthesis method of dihydropyrimidinone compounds | 宜春学院 | 2021-05-18 | — | — | CN | disclosed |
| WO-2017134188-A1 | NOVEL DIHYDROPYRIDINONE AND DIHYDROPYRIMIDINONE COMPOUNDS AND THEIR USE | UNIVERSITE DE LILLE 2 DROIT ET SANTE (FR) | 2017-08-10 | — | — | WO | disclosed |
| WO-2017134188-A1 | NOVEL DIHYDROPYRIDINONE AND DIHYDROPYRIMIDINONE COMPOUNDS AND THEIR USE | UNIVERSITE DE LILLE 2 DROIT ET SANTE (FR) | 2017-08-10 | — | — | WO | disclosed |
| WO-2007101213-A2 | NOVEL 2-OXO-1,2,3,4-TETRAHYDROPYRIMIDINES, BICYCLIC PYRIMIDINE DIONES AND IMIDAZOLIDINE-2,4-DIONES USEFUL AS INDUCIBLE NITRIC OXIDE SYNTHASE INHIBITORS | KALYPSYS, INC. (US) | 2007-09-07 | — | — | WO | disclosed |
| WO-2007101213-A2 | NOVEL 2-OXO-1,2,3,4-TETRAHYDROPYRIMIDINES, BICYCLIC PYRIMIDINE DIONES AND IMIDAZOLIDINE-2,4-DIONES USEFUL AS INDUCIBLE NITRIC OXIDE SYNTHASE INHIBITORS | KALYPSYS, INC. (US) | 2007-09-07 | — | — | WO | disclosed |