Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT2 | P31751 | 6/20 | 0.47 |
| ▸ | AKT1 | P31749 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.41 |
| ▸ | TUBB | P07437 | 1/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.41 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.41 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.41 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.41 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.41 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.41 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.41 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.41 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5337928 | 0.94 | AKT1 (0.52) | AKT2AKT1KDM4ECASP1CASP7 | |
| SCHEMBL5478849 | 0.91 | AKT1 (0.55) | AKT2AKT1KDM4ECASP1CASP7 | |
| SCHEMBL5318511 | 0.86 | AURKA (0.55) | AKT2AKT1TUBB4ATUBBTUBA3C | |
| SCHEMBL5340752 | 0.84 | CNR1 (0.53) | AKT2AKT1TUBB4ATUBBTUBA3C | |
| SCHEMBL5335616 | 0.83 | AKT1 (0.45) | AKT2AKT1MCL1DHODHAURKA | |
| SCHEMBL5443619 | 0.83 | AKT2 (0.52) | AKT2AKT1MCL1DHODHAURKA | |
| SCHEMBL5341397 | 0.83 | AKT1 (0.45) | AKT2AKT1MCL1DHODHAURKA | |
| SCHEMBL5340645 | 0.83 | AKT1 (0.54) | AKT2AKT1KDM4ECASP1CASP7 | |
| SCHEMBL5440820 | 0.81 | CNR1 (0.43) | AKT2AKT1KDM4ECASP1CASP7 | |
| SCHEMBL5318509 | 0.81 | CNR1 (0.55) | GRIA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007086080-A2 | NOVEL IMIDAZO[1,2-a]PYRIDINE CANNABINOID RECEPTOR LIGANDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2007-08-02 | — | — | WO | disclosed |