Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 6/20 | 0.52 |
| ▸ | AKT2 | P31751 | 6/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | CASP7 | P55210 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | GRIA1 | P42261 | 4/20 | 0.44 |
| ▸ | DHODH | Q02127 | 2/20 | 0.43 |
| ▸ | CACNG2 | Q9Y698 | 1/20 | 0.42 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.42 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.42 |
| ▸ | TSPO | P30536 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5478849 | 0.97 | AKT1 (0.55) | AKT1AKT2KDM4ECASP1CASP7 | |
| SCHEMBL5341869 | 0.94 | AKT2 (0.47) | AKT1AKT2KDM4ECASP1CASP7 | |
| SCHEMBL5340645 | 0.88 | AKT1 (0.54) | AKT1AKT2KDM4ECASP1CASP7 | |
| SCHEMBL5440820 | 0.87 | CNR1 (0.43) | AKT1AKT2KDM4ECASP1CASP7 | |
| SCHEMBL5337716 | 0.83 | CNR1 (0.55) | AKT1AKT2KDM4ECASP1CASP7 | |
| SCHEMBL5348576 | 0.82 | AKT1 (0.65) | AKT1AKT2TSPO | |
| SCHEMBL5340360 | 0.81 | AKT1 (0.46) | AKT1AKT2TSPO | |
| SCHEMBL5318511 | 0.80 | AURKA (0.55) | AKT1AKT2 | |
| SCHEMBL5340752 | 0.78 | CNR1 (0.53) | AKT1AKT2GRIA1TSPO | |
| SCHEMBL17004138 | 0.77 | AKT2 (0.86) | AKT1AKT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007086080-A2 | NOVEL IMIDAZO[1,2-a]PYRIDINE CANNABINOID RECEPTOR LIGANDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2007-08-02 | — | — | WO | claimed |
| WO-2007086080-A2 | NOVEL IMIDAZO[1,2-a]PYRIDINE CANNABINOID RECEPTOR LIGANDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2007-08-02 | — | — | WO | disclosed |