Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL979256 | 0.89 | CYP3A4 (0.35) | CYP3A4POLBMAPT | |
| SCHEMBL1754879 | 0.89 | CYP3A4 (0.35) | CYP3A4POLBMAPT | |
| Hydrochloric Acid SCHEMBL2898888 | 0.87 | CYP3A4 (0.34) | CYP3A4POLBMAPT | |
| SCHEMBL16611660 | 0.79 | SLC6A2 (0.38) | SLC6A2SLC6A4SLC6A3SMN1; SMN2 | |
| SCHEMBL3765643 | 0.77 | — | — | |
| SCHEMBL1528190 | 0.77 | SMN1; SMN2 (0.46) | CYP3A4POLBSMN1; SMN2MAPT | |
| Water SCHEMBL7155879 | 0.76 | CYP3A4 (0.37) | CYP3A4POLB | |
| SCHEMBL30616319 | 0.76 | SLC6A2 (0.38) | SLC6A2SLC6A4SLC6A3SMN1; SMN2MAPT | |
| SCHEMBL30762 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL7162864 | 0.73 | PIK3CD (0.47) | CHRM2CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1853569-A1 | LIGANDS FOR G-PROTEIN COUPLED RECEPTORS | Cambridge Enterprise Limited (GB) | 2007-11-14 | — | — | EP | disclosed |
| WO-2006085096-A1 | LIGANDS FOR G-PROTEIN COUPLED RECEPTORS | CAMBRIDGE ENTERPRISE LIMITED (GB) | 2006-08-17 | — | — | WO | disclosed |