Sugi Predict

Sugi Predict / Compounds / SCHEMBL5342247

SCHEMBL5342247

SCHEMBL5342247

COC(=O)C1(Cc2ccc(Cl)cc2)CCC(C)(C)C1=O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TACR1 P25103 1/20 0.44
▸ TACR3 P29371 1/20 0.44
▸ ALDH1A1 P00352 7/20 0.39
▸ SMN1; SMN2 Q16637 2/20 0.39
▸ POLB P06746 1/20 0.37
▸ MEN1 O00255 3/20 0.37
▸ KMT2A Q03164 3/20 0.37
▸ SSTR1 P30872 1/20 0.35
▸ SSTR4 P31391 1/20 0.35
▸ NPC1 O15118 1/20 0.34
▸ RAB9A P51151 1/20 0.34
▸ LMNA P02545 2/20 0.34
▸ MAPT P10636 2/20 0.34
▸ HDAC1 Q13547 1/20 0.34
▸ HDAC6 Q9UBN7 1/20 0.34
▸ OPRL1 P41146 1/20 0.34
▸ KDM4E B2RXH2 1/20 0.34
▸ TNF P01375 1/20 0.34
▸ HSP90AA1 P07900 1/20 0.34
▸ HPGD P15428 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5347064 0.87 POLB (0.48) ALDH1A1SMN1; SMN2POLBMEN1KMT2A
SCHEMBL8830686 0.86 MEN1 (0.36) ALDH1A1SMN1; SMN2POLBMEN1KMT2A
SCHEMBL15641227 0.86 TACR1 (0.40) TACR1TACR3ALDH1A1SMN1; SMN2POLB
SCHEMBL9265932 0.86 TACR1 (0.40) TACR1TACR3ALDH1A1SMN1; SMN2POLB
SCHEMBL2030628 0.86 TACR1 (0.40) TACR1TACR3ALDH1A1SMN1; SMN2POLB
SCHEMBL16473222 0.85 TACR1 (0.41) TACR1TACR3ALDH1A1SMN1; SMN2POLB
SCHEMBL2035975 0.85 TACR1 (0.41) TACR1TACR3ALDH1A1SMN1; SMN2POLB
SCHEMBL15641445 0.85 TACR1 (0.41) TACR1TACR3ALDH1A1SMN1; SMN2POLB
SCHEMBL17589774 0.85 TACR1 (0.39) TACR1TACR3ALDH1A1SMN1; SMN2POLB
SCHEMBL6052833 0.85 ALDH1A1 (0.37) ALDH1A1POLBMEN1KMT2ASSTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119080616-A Preparation method of 1- (4-chlorobenzyl) -3, 3-dimethyl-2-oxo-cyclopentanecarboxylic acid methyl ester 内蒙古冠仕达化学有限公司 2024-12-06 — — CN claimed
US-7166750-B1 Process for the preparation of 5-[(4-chlorophenyl)methyl]-2,2-dimethylcyclopentanone KUREHA CORPORATION (JP) 2007-01-23 — — US claimed
EP-1308432-B1 PROCESS FOR THE PREPARATION OF 5- (4-CHLOROPHENYL)-METHYL|-2,2-DIMETHYLCYCLOPENTANONE KUREHA CORP (JP) 2006-10-18 — — EP claimed
EP-1308432-A1 PROCESS FOR THE PREPARATION OF 5- (4-CHLOROPHENYL)-METHYL]-2,2-DIMETHYLCYCLOPENTANONE KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2003-05-07 — — EP claimed
CN-119080616-A Preparation method of 1- (4-chlorobenzyl) -3, 3-dimethyl-2-oxo-cyclopentanecarboxylic acid methyl ester 内蒙古冠仕达化学有限公司 2024-12-06 — — CN disclosed
CN-119080616-A Preparation method of 1- (4-chlorobenzyl) -3, 3-dimethyl-2-oxo-cyclopentanecarboxylic acid methyl ester 内蒙古冠仕达化学有限公司 2024-12-06 — — CN disclosed
CN-119080616-A Preparation method of 1- (4-chlorobenzyl) -3, 3-dimethyl-2-oxo-cyclopentanecarboxylic acid methyl ester 内蒙古冠仕达化学有限公司 2024-12-06 — — CN disclosed
CN-104591989-B The preparation method of 5 [(4 chlorphenyl) methyl] 2,2 cyclopentanone dimethyls 上海华谊（集团）公司 2017-08-29 — — CN disclosed
US-9206106-B2 Production method of carbonyl compound KUREHA CORPORATION (JP) 2015-12-08 — — US disclosed
US-20150299080-A1 PRODUCTION METHOD OF CARBONYL COMPOUND KUREHA CORPORATION (JP) 2015-10-22 — — US disclosed
EP-2927207-A1 PRODUCTION METHOD FOR CARBONYL COMPOUND Kureha Corporation (JP) 2015-10-07 — — EP disclosed
CN-104684881-A Process for producing carbonyl compound KUREHA CORP 2015-06-03 — — CN disclosed
EP-0731083-A1 Process for the producing of alkylcyclopentanone derivatives KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1996-09-11 — — EP disclosed
US-5414105-A Alkyl esters of benzyl-substituted 2-oxocyclopentanecarboxylic acids; azoles have plant disease controlling and plant growth regulating activity KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1995-05-09 — — US disclosed
US-5239089-A Plant growth controllers KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1993-08-24 — — US disclosed
EP-0267778-B1 AZOLE DERIVATIVES USEFUL IN CONTROLLING PLANT DISEASES AND REGULATING PLANT GROWTH KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1993-03-24 — — EP disclosed
US-5159118-A Chemical intermediate; controlling plant diseases, plant growth regulators, fungicides KUREHA KAGAKU KABUSHIKI KAISHA (JP) 1992-10-27 — — US disclosed
US-5028254-A Fungicides, plant growth regulators KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1991-07-02 — — US disclosed
US-4938792-A Fungicide, plant growth regulator KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1990-07-03 — — US disclosed
EP-0267778-A2 Azole derivatives useful in controlling plant diseases and regulating plant growth KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1988-05-18 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150299080-A1 PRODUCTION METHOD OF CARBONYL COMPOUND CBR3, CBR1, PAH TACR1 146/4885TACR3 1209/4885ALDH1A1 208/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.