Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 5/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.37 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.37 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.37 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9016945 | 0.86 | CA2 (0.40) | CA2MAPK1ALDH1A1CYP3A4TSHR | |
| SCHEMBL5475897 | 0.83 | CA2 (0.41) | CA2MAPK1ALDH1A1CYP3A4TSHR | |
| SCHEMBL16712426 | 0.79 | CA2 (0.40) | CA2MAPK1ALDH1A1CYP3A4TSHR | |
| SCHEMBL5482192 | 0.77 | CA2 (0.38) | CA2MAPK1ALDH1A1CYP3A4TSHR | |
| SCHEMBL186951 | 0.77 | RECQL (0.42) | CA2MAPK1ALDH1A1CYP3A4TSHR | |
| SCHEMBL465484 | 0.76 | CA2 (0.46) | CA2MAPK1ALDH1A1CYP3A4TSHR | |
| Ammonia Solution, Strong SCHEMBL3702920 | 0.76 | RECQL (0.41) | CA2MAPK1ALDH1A1CYP3A4TSHR | |
| SCHEMBL5475669 | 0.76 | CA2 (0.41) | CA2MAPK1ALDH1A1CYP3A4TSHR | |
| Ammonia Solution, Strong SCHEMBL3975597 | 0.76 | RECQL (0.41) | CA2MAPK1ALDH1A1CYP3A4TSHR | |
| SCHEMBL3695354 | 0.76 | RECQL (0.41) | CA2MAPK1ALDH1A1CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7312266-B2 | Organic thiol metal-free stabilizers and plasticizers for halogen-containing polymers | THE COLLEGE OF WILLIAM AND MARY (US) | 2007-12-25 | — | — | US | disclosed |