Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL535073 | 1.00 | TSHR (0.48) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL1286178 | 0.96 | TSHR (0.52) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL4446247 | 0.88 | TSHR (0.44) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL4446614 | 0.88 | TSHR (0.44) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL12199987 | 0.85 | TSHR (0.59) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL13024783 | 0.85 | TSHR (0.48) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL1537080 | 0.85 | TSHR (0.48) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL28389252 | 0.84 | TSHR (0.52) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL149836 | 0.84 | TSHR (0.47) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL30360186 | 0.83 | TSHR (0.50) | TSHRALDH1A1TP53HIF1ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2276781-B1 | ETHYLENE-TETRAFLUOROETHYLENE INTERMEDIATES | DU PONT (US) | 2012-11-07 | — | — | EP | claimed |
| US-8212064-B2 | Ethylene tetrafluoroethylene intermediates | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-07-03 | — | — | US | claimed |
| US-20090287010-A1 | Ethylene-tetrafluoroethylene intermediates | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-11-19 | — | — | US | claimed |
| US-8318877-B2 | Ethylene tetrafluoroethylene (meth)acrylate copolymers | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-11-27 | — | — | US | disclosed |
| US-8314037-B2 | Fluoropolymer emulsions | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-11-20 | — | — | US | disclosed |
| EP-2276781-B1 | ETHYLENE-TETRAFLUOROETHYLENE INTERMEDIATES | DU PONT (US) | 2012-11-07 | — | — | EP | disclosed |
| US-8212064-B2 | Ethylene tetrafluoroethylene intermediates | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-07-03 | — | — | US | disclosed |
| EP-2217630-B1 | FLUOROPOLYMER EMULSIONS | DU PONT (US) | 2012-02-29 | — | — | EP | disclosed |
| EP-2283051-B1 | ETHYLENE TETRAFLUOROETHYLENE (METH)ACRYLATE COPOLYMERS | DU PONT (US) | 2012-02-08 | — | — | EP | disclosed |
| EP-2283051-A1 | ETHYLENE TETRAFLUOROETHYLENE (METH)ACRYLATE COPOLYMERS | E. I. du Pont de Nemours and Company (US) | 2011-02-16 | — | — | EP | disclosed |
| WO-2009143194-A1 | ETHYLENE TETRAFLUOROETHYLENE (METH)ACRYLATE COPOLYMERS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-11-26 | — | — | WO | disclosed |
| US-20090291222-A1 | Ethylene tetrafluoroethylene (meth)acrylate copolymers | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-11-26 | — | — | US | disclosed |
| US-20090287010-A1 | Ethylene-tetrafluoroethylene intermediates | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-11-19 | — | — | US | disclosed |
| US-20090149096-A1 | FLUOROPOLYMER EMULSIONS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-06-11 | — | — | US | disclosed |
| US-20090148653-A1 | FLUOROPOLYMER EMULSIONS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-06-11 | — | — | US | disclosed |