SCHEMBL1286178

SCHEMBL1286178

C=CC(=O)OCCC(F)(F)C(F)(F)F

nearest known ligand 0.52

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.52
ALDH1A1 P00352 4/20 0.52
TP53 P04637 3/20 0.52
HIF1A Q16665 3/20 0.52
CYP3A4 P08684 2/20 0.52
HSD17B10 Q99714 1/20 0.52
HPGD P15428 1/20 0.47
THRB P10828 2/20 0.43
MAPK1 P28482 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL535073 0.96 TSHR (0.48) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL534356 0.96 TSHR (0.48) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL12199987 0.89 TSHR (0.59) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL1537080 0.89 TSHR (0.48) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL13024783 0.89 TSHR (0.48) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL149836 0.87 TSHR (0.47) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL30360186 0.86 TSHR (0.50) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL18188003 0.86 TSHR (0.43) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL708916 0.85 TSHR (0.46) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL709253 0.85 TSHR (0.46) TSHRALDH1A1TP53HIF1ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 135 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3575334-B1 MOLDING MATERIAL AND METHOD FOR PRODUCING RESIN MOLDED BODY USING SAME UNIV OSAKA (JP) 2023-05-24 EP claimed
US-11623975-B2 Molding material and method for producing resin molded body using same OSAKA UNIVERSITY (JP) 2023-04-11 US claimed
CN-112646418-A Quantum dot ink, preparation method of quantum dot light-emitting diode and display device 广东聚华印刷显示技术有限公司 2021-04-13 CN claimed
US-20260128194-A1 ELECTRIC WIRE, METHOD FOR PRODUCING ELECTRIC WIRE, AND MASTERBATCH DAIKIN AMERICA, INC. (US) 2026-05-07 US disclosed
EP-3688046-B1 COPOLYMERS OF HALOGENATED OLEFINS AND HALOGENATED CO-MONOMERS ARKEMA INC (US) 2026-01-07 EP disclosed
EP-3919250-B1 MOLD RELEASE AGENT DAIKIN IND LTD (JP) 2025-08-06 EP disclosed
US-12151406-B2 Mold release agent DAIKIN INDUSTRIES, LTD. (JP) 2024-11-26 US disclosed
CN-118382418-A Cosmetic composition comprising polyhydroxyalkanoate copolymer with (unsaturated) hydrocarbon-based chain and silicone polymer 欧莱雅 2024-07-23 CN disclosed
EP-3435962-B1 DEVICE FOR APPLYING A COMPOSITION IN THE FORM OF AN EMULSION COMPRISING A FILM-FORMING AGENT AND NON-VOLATILE OILS OREAL (FR) 2024-05-22 EP disclosed
EP-3435963-B1 EMULSION COMPRISING A FILM-FORMING AGENT AND NON-VOLATILE OILS AND COSMETIC PROCESS OREAL (FR) 2024-05-01 EP disclosed
US-20240101754-A1 DUAL CURING COMPOSITION BASED ON ACRYLATE FUNCTIONAL COMPOUNDS HENKEL AG & CO KGAA (DE) 2024-03-28 US disclosed
EP-1475397-A1 BLOCK COPOLYMER KANEKA CORPORATION (JP) 2004-11-10 EP disclosed
EP-1455200-A1 PRECURSOR COMPOSITION FOR OPTICAL RESIN, RESIN FOR OPTICAL USE, OPTICAL ELEMENT, AND OPTICAL ARTICLE Nikon Corporation (JP) 2004-09-08 EP disclosed
US-20040147674-A1 Thermoplastic resin composition KANEKA CORPORATION (JP) 2004-07-29 US disclosed
EP-1440680-A1 COSMETIC POLYMER COMPOSITION AND COSMETIC Mitsubishi Chemical Corporation (JP) 2004-07-28 EP disclosed
EP-1398353-A1 THERMOPLASTIC RESIN COMPOSITION Kaneka Corporation (JP) 2004-03-17 EP disclosed
US-6534594-B1 Methacrylate-siloxane block copolymer; impact strength KANEKA CORPORATION (JP) 2003-03-18 US disclosed
EP-1179566-A1 ELASTOMER COMPOSITION AND THERMOPLASTIC RESIN COMPOSITION CONTAINING THE SAME KANEKA CORPORATION (JP) 2002-02-13 EP disclosed
US-5919532-A Active matrix substrate, method for fabricating the same, and liquid crystal display device SHARP KABUSHIKI KAISHA (JP) 1999-07-06 US disclosed
US-5908721-A COLOR FILTER SHARP KABUSHIKI KAISHA (JP) 1999-06-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260128194-A1 ELECTRIC WIRE, METHOD FOR PRODUCING ELECTRIC WIRE, AND MASTERBATCH PRDM7, EED, PRDM9 TSHR 2799/4885ALDH1A1 4213/4885TP53 4247/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.