Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.30 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.30 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8951817 | 0.78 | LMNA (0.34) | LMNA | |
| SCHEMBL5351940 | 0.75 | LMNA (0.43) | LMNA | |
| SCHEMBL5339523 | 0.70 | LMNA (0.45) | LMNAPRSS1PRSS2PRSS3 | |
| SCHEMBL5343751 | 0.69 | LMNA (0.37) | LMNAPRSS1PRSS2PRSS3 | |
| SCHEMBL25125871 | 0.62 | LMNA (0.68) | LMNA | |
| SCHEMBL20746400 | 0.62 | LMNA (0.68) | LMNA | |
| SCHEMBL20746351 | 0.62 | LMNA (0.68) | LMNA | |
| SCHEMBL20746348 | 0.62 | LMNA (0.68) | LMNA | |
| SCHEMBL21996120 | 0.62 | LMNA (0.68) | LMNA | |
| SCHEMBL20746187 | 0.62 | LMNA (0.68) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016130460-A9 | PHTHALAZINONE PYRAZOLE DERIVATIVES FOR TREATING RETINAL DEGENERATIVE DISEASE | THE JOHNS HOPKINS UNIVERSITY (US) | 2016-09-15 | — | — | WO | claimed |
| EP-1794148-A1 | NOVEL PHTHALAZINONE DERIVATIVES, AS AURORA-A KINASE INHIBITORS | F.HOFFMANN-LA ROCHE AG (CH) | 2007-06-13 | — | — | EP | claimed |
| WO-2006032518-A1 | NOVEL PHTHALAZINONE DERIVATIVES, AS AURORA-A KINASE INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2006-03-30 | — | — | WO | claimed |
| EP-0441460-B1 | Cyclopentadienes, their manufacture and lubricating compositions containing them | PENNZOIL PROD CO (US) | 1996-11-20 | — | — | EP | claimed |
| EP-0441460-A2 | Cyclopentadienes, their manufacture and lubricating compositions containing them | PENNZOIL PRODUCTS COMPANY (US) | 1991-08-14 | — | — | EP | claimed |
| US-4849566-A | Lubricants comprising novel cyclopentanes, cyclopentadienes, cyclopentenes, and mixtures thereof and methods of manufacture | PENNZOIL PRODUCTS COMPANY (US) | 1989-07-18 | — | — | US | claimed |
| US-7244522-B2 | For use in data recording/ retrieval device | SHELL OIL COMPANY (US) | 2007-07-17 | — | — | US | disclosed |
| EP-1794148-A1 | NOVEL PHTHALAZINONE DERIVATIVES, AS AURORA-A KINASE INHIBITORS | F.HOFFMANN-LA ROCHE AG (CH) | 2007-06-13 | — | — | EP | disclosed |
| US-7195828-B2 | Lubricant for magnetic recording medium and use thereof | SHELL OIL COMPANY (US) | 2007-03-27 | — | — | US | disclosed |
| EP-1454316-B1 | LUBRICANT FOR MAGNETIC RECORDING MEDIUM AND USE THEREOF | PENNZOIL QUAKER STATE CO (US) | 2006-08-09 | — | — | EP | disclosed |
| WO-2006032518-A1 | NOVEL PHTHALAZINONE DERIVATIVES, AS AURORA-A KINASE INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2006-03-30 | — | — | WO | disclosed |
| US-20060035113-A1 | Lubricant for magnetic recording medium and use thereof | GUNSEL SELDA | 2006-02-16 | — | — | US | disclosed |
| EP-1454316-A2 | LUBRICANT FOR MAGNETIC RECORDING MEDIUM AND USE THEREOF | Pennzoil-Quaker State Company (US) | 2004-09-08 | — | — | EP | disclosed |
| WO-2000058956-A1 | LUBRICANT FOR MAGNETIC RECORDING MEDIUM AND USE THEREOF | PENNZOIL-QUAKER STATE COMPANY (US) | 2000-10-05 | — | — | WO | disclosed |
| EP-0441460-B1 | Cyclopentadienes, their manufacture and lubricating compositions containing them | PENNZOIL PROD CO (US) | 1996-11-20 | — | — | EP | disclosed |
| EP-0441460-A2 | Cyclopentadienes, their manufacture and lubricating compositions containing them | PENNZOIL PRODUCTS COMPANY (US) | 1991-08-14 | — | — | EP | disclosed |
| US-5012023-A | Lubricants comprising novel cyclopentanes, cyclopentadienes, cyclopentenes, and mixtures thereof and methods of manufacture | PENNZOIL PRODUCTS COMPANY (US) | 1991-04-30 | — | — | US | disclosed |
| US-5012022-A | Lubricants comprising novel cyclopentanes, cyclopentadienes, cyclopentenes, and mixtures thereof and methods of manufacture | PENNZOIL PRODUCTS COMPANY (US) | 1991-04-30 | — | — | US | disclosed |
| US-4929782-A | BASIC CATALYSTS, ALKYLATION, DEHYDRATION | PENNZOIL PRODUCTS COMPANY (US) | 1990-05-29 | — | — | US | disclosed |
| US-4849566-A | Lubricants comprising novel cyclopentanes, cyclopentadienes, cyclopentenes, and mixtures thereof and methods of manufacture | PENNZOIL PRODUCTS COMPANY (US) | 1989-07-18 | — | — | US | disclosed |