Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 4/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 4/20 | 0.48 |
| ▸ | TP53 | P04637 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | CDK4 | P11802 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | CCND1 | P24385 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5848569 | 0.81 | SLC6A2 (0.52) | SLC6A2SLC6A4GAATP53MAPT | |
| SCHEMBL10802819 | 0.79 | SLC6A2 (0.54) | SLC6A2SLC6A4GAATP53MAPT | |
| SCHEMBL5847681 | 0.79 | SLC6A2 (0.54) | SLC6A2SLC6A4GAATP53MAPT | |
| SCHEMBL25112007 | 0.78 | SLC6A2 (0.49) | SLC6A2SLC6A4GAATP53MAPT | |
| SCHEMBL11852260 | 0.78 | GAA (0.47) | SLC6A2SLC6A4GAATP53MAPT | |
| SCHEMBL1963702 | 0.75 | MAPT (0.58) | SLC6A2SLC6A4GAATP53MAPT | |
| SCHEMBL17652441 | 0.75 | SLC6A2 (0.47) | SLC6A2SLC6A4GAATP53MAPT | |
| SCHEMBL11729757 | 0.74 | SLC6A2 (0.46) | SLC6A2SLC6A4GAATP53MAPT | |
| SCHEMBL463221 | 0.74 | SLC6A2 (0.42) | SLC6A2SLC6A4GAATP53MAPT | |
| SCHEMBL25333374 | 0.74 | SLC6A2 (0.43) | SLC6A2SLC6A4GAATP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2414323-A1 | DERIVATIVES OF AMINOCYCLOBUTANE OR AMINOCYCLOBUTENE, THEIR METHOD OF PREPARATION AND THEIR USE AS MEDICAL PRODUCTS | Pierre Fabre Médicament (FR) | 2012-02-08 | — | — | EP | disclosed |