Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | CDK4 | P11802 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CCND1 | P24385 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL463221 | 0.83 | SLC6A2 (0.42) | SLC6A2SLC6A4NPC1RAB9AALDH1A1 | |
| SCHEMBL19953534 | 0.79 | MEN1 (0.42) | SLC6A2SLC6A4NPC1RAB9AALDH1A1 | |
| SCHEMBL27675115 | 0.79 | NOTUM (0.45) | SLC6A2SLC6A4L3MBTL1ALDH1A1MEN1 | |
| SCHEMBL27463313 | 0.79 | ALDH1A1 (0.42) | SLC6A2SLC6A4NPC1RAB9AALDH1A1 | |
| SCHEMBL307372 | 0.79 | NOTUM (0.45) | NPC1RAB9AL3MBTL1ALDH1A1MEN1 | |
| SCHEMBL28292118 | 0.77 | MAPT (0.48) | SLC6A2SLC6A4NPC1RAB9AL3MBTL1 | |
| SCHEMBL11852260 | 0.77 | GAA (0.47) | SLC6A2SLC6A4ALDH1A1MEN1KMT2A | |
| SCHEMBL25112007 | 0.77 | SLC6A2 (0.49) | SLC6A2SLC6A4NPC1RAB9AL3MBTL1 | |
| SCHEMBL23723712 | 0.76 | SLC6A2 (0.46) | SLC6A2SLC6A4NPC1RAB9AALDH1A1 | |
| SCHEMBL534412 | 0.74 | SLC6A2 (0.50) | SLC6A2SLC6A4NPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023144793-A1 | POL THETA INHIBITORS | RHIZEN PHARMACEUTICALS AG (CH) | 2023-08-03 | — | — | WO | disclosed |