Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | S100A4 | P26447 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | TDP2 | O95551 | 1/20 | 0.37 |
| ▸ | AHR | P35869 | 1/20 | 0.35 |
| ▸ | PTPRC | P08575 | 1/20 | 0.34 |
| ▸ | METAP1 | P53582 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3456628 | 0.81 | PBRM1 (0.40) | CA1CA2CA4CA7CA9 | |
| SCHEMBL9136839 | 0.77 | PKM (0.47) | CYP19A1MAOB | |
| SCHEMBL5318615 | 0.73 | BACE1 (0.41) | CA1CA2CA4CA7CA9 | |
| SCHEMBL8834065 | 0.72 | HTR2A (0.47) | S100A4HTR2AHTR2CPBRM1HTT | |
| SCHEMBL9136416 | 0.71 | CYP19A1 (0.32) | CYP19A1LMNAMAOB | |
| SCHEMBL9135853 | 0.71 | MAOB (0.42) | S100A4CYP19A1MAPTTDP1MAOB | |
| SCHEMBL9135908 | 0.71 | FABP6 (0.46) | CA1CA2CA7CA9CYP19A1 | |
| SCHEMBL24697708 | 0.71 | MGAT2 (0.44) | HTR2AHTR2CPBRM1HTTTDP2 | |
| SCHEMBL1429041 | 0.71 | MAOB (0.46) | S100A4HTR2AHTR2CPBRM1CYP19A1 | |
| SCHEMBL2066249 | 0.68 | MAOB (0.64) | HTR2AHTR2CLMNAMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007088450-A2 | CHROMANE ANTAGONIST OF THE H-3 RECEPTOR | PFIZER PRODUCTS INC. (US) | 2007-08-09 | — | — | WO | disclosed |