Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 5/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | EED | O75530 | 2/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.45 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | AGXT | P21549 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27730804 | 0.79 | EED (0.66) | SLC6A4HTR1AEEDIDO1AGXT | |
| SCHEMBL25698257 | 0.76 | EED (0.71) | SLC6A4HTR1AEEDIDO1AGXT | |
| SCHEMBL4665743 | 0.76 | SLC6A4 (0.41) | SLC6A4HTR1AEEDSLC6A2OPRM1 | |
| SCHEMBL5346621 | 0.76 | EED (0.58) | SLC6A4HTR1AEEDIDO1AGXT | |
| SCHEMBL4665394 | 0.75 | OPRK1 (0.65) | SLC6A4SLC6A2OPRM1SLC22A1MEN1 | |
| SCHEMBL4663468 | 0.74 | SLC6A4 (0.53) | SLC6A4HTR1AEEDSLC6A2OPRM1 | |
| SCHEMBL4664145 | 0.74 | OPRK1 (0.58) | SLC6A4SLC6A2OPRM1SLC22A1MEN1 | |
| SCHEMBL4663491 | 0.74 | SLC6A4 (0.47) | SLC6A4HTR1AEEDSLC6A2OPRM1 | |
| SCHEMBL4663417 | 0.74 | SLC6A4 (0.47) | SLC6A4HTR1AEEDSLC6A2OPRM1 | |
| SCHEMBL13681485 | 0.74 | EED (0.59) | SLC6A4HTR1AEEDIDO1AGXT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7273952-B2 | Substituted C-cyclohexylmethylamine derivatives | GRUENENTHAL GMBH (DE) | 2007-09-25 | — | — | US | disclosed |