Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 7/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5486486 | 0.79 | TRPV1 (0.53) | TRPV1 | |
| SCHEMBL5275717 | 0.76 | TRPV1 (0.47) | TRPV1 | |
| SCHEMBL5420464 | 0.76 | EPHX2 (0.40) | TRPV1 | |
| SCHEMBL5354441 | 0.74 | TRPV1 (0.47) | TRPV1 | |
| SCHEMBL5223625 | 0.74 | TRPV1 (0.38) | TRPV1 | |
| SCHEMBL5274596 | 0.72 | TRPV1 (0.52) | TRPV1 | |
| SCHEMBL5177718 | 0.70 | PPARG (0.53) | — | |
| SCHEMBL5276273 | 0.68 | TRPV1 (0.68) | TRPV1 | |
| SCHEMBL5273647 | 0.68 | TRPV1 (0.65) | TRPV1 | |
| SCHEMBL5277757 | 0.68 | TRPV1 (0.68) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007120012-A1 | NOVEL COMPOUNDS, ISOMER THEREOF, OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF AS VANILLOID RECEPTOR ANTAGONIST; AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | AMOREPACIFIC CORPORATION (KR) | 2007-10-25 | — | — | WO | disclosed |