Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4641751 | 0.77 | TRPV1 (0.46) | TRPV1 | |
| SCHEMBL5084741 | 0.75 | MAPT (0.39) | — | |
| SCHEMBL5322958 | 0.75 | PPARG (0.44) | TRPV1 | |
| SCHEMBL5345312 | 0.74 | TRPV1 (0.43) | TRPV1 | |
| SCHEMBL5354441 | 0.74 | TRPV1 (0.47) | TRPV1 | |
| SCHEMBL5486486 | 0.72 | TRPV1 (0.53) | TRPV1 | |
| SCHEMBL4640570 | 0.72 | MEN1 (0.45) | TRPV1 | |
| SCHEMBL5420464 | 0.71 | EPHX2 (0.40) | TRPV1 | |
| SCHEMBL5402944 | 0.71 | TRPV1 (0.38) | TRPV1 | |
| SCHEMBL4641594 | 0.69 | TRPV1 (0.54) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1824837-A1 | SUBSTITUTED N-SULFONYLAMINOBENZYL-2-PHENOXY ACETAMIDE COMPOUNDS | Pfizer, Inc. (US) | 2007-08-29 | — | — | EP | disclosed |
| WO-2006051378-A1 | SUBSTITUTED N-SULFONYLAMINOBENZYL-2-PHENOXY ACETAMIDE COMPOUNDS | PFIZER JAPAN INC. (JP) | 2006-05-18 | — | — | WO | disclosed |