Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.50 |
| ▸ | CDK4 | P11802 | 1/20 | 0.50 |
| ▸ | CCND1 | P24385 | 1/20 | 0.50 |
| ▸ | JUN | P05412 | 1/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 3/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.46 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.46 |
| ▸ | ECE2 | P0DPD6 | 2/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
| ▸ | BCR | P11274 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | GUSB | P08236 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5345374 | 1.00 | TRPA1 (0.52) | TRPA1MAPTLMNANFKB1CDK4 | |
| SCHEMBL7021759 | 0.83 | MAPT (0.48) | TRPA1MAPTLMNANFKB1CDK4 | |
| SCHEMBL7030080 | 0.83 | MAPT (0.48) | TRPA1MAPTLMNANFKB1CDK4 | |
| SCHEMBL7021762 | 0.83 | MAPT (0.48) | TRPA1MAPTLMNANFKB1CDK4 | |
| SCHEMBL7030075 | 0.83 | MAPT (0.48) | TRPA1MAPTLMNANFKB1CDK4 | |
| SCHEMBL433097 | 0.82 | MAPT (0.47) | TRPA1MAPTLMNANFKB1CDK4 | |
| SCHEMBL433096 | 0.82 | MAPT (0.47) | TRPA1MAPTLMNANFKB1CDK4 | |
| SCHEMBL108389 | 0.78 | TRPA1 (0.76) | TRPA1MAPTLMNANFKB1CDK4 | |
| SCHEMBL717976 | 0.78 | TRPA1 (0.76) | TRPA1MAPTLMNANFKB1CDK4 | |
| SCHEMBL28763783 | 0.78 | MAPT (0.47) | TRPA1MAPTLMNANFKB1CDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7291692-B2 | Polyarylene oxide and method of producing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-11-06 | — | — | US | disclosed |
| US-20050096452-A1 | Polyarylene oxide and method of producing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2005-05-05 | — | — | US | disclosed |