Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2317665 | 0.82 | BRD4 (0.31) | BRD4 | |
| SCHEMBL1885979 | 0.79 | CDK5 (0.38) | BRD4 | |
| SCHEMBL14158908 | 0.78 | KDR (0.32) | — | |
| SCHEMBL12147002 | 0.76 | HTR2A (0.30) | — | |
| SCHEMBL17817725 | 0.76 | — | — | |
| SCHEMBL14158619 | 0.76 | CDK5 (0.35) | — | |
| SCHEMBL415255 | 0.72 | ELANE (0.42) | BRD4 | |
| SCHEMBL1880922 | 0.72 | BRD4 (0.37) | BRD4 | |
| SCHEMBL794853 | 0.70 | MGAM (0.34) | — | |
| SCHEMBL29660466 | 0.70 | MGAM (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007106236-A2 | PYRROLO-PYRIDINE KINASE MODULATORS | SGX PHARMACEUTICALS, INC. (US) | 2007-09-20 | — | — | WO | disclosed |