SCHEMBL29660466

SCHEMBL29660466

CC(C)[Si](C(C)C)(C(C)C)n1ccc2c(Br)ccnc21

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MGAM O43451 1/20 0.34
GAA P10253 1/20 0.34
SI P14410 1/20 0.34
MGAM2 Q2M2H8 1/20 0.34
PRKCI P41743 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL794853 1.00 MGAM (0.34) MGAMGAASIMGAM2PRKCI
SCHEMBL15155025 0.98 MGAM (0.34) MGAMGAASIMGAM2PRKCI
SCHEMBL15155026 0.97 MGAM (0.33) MGAMGAASIMGAM2PRKCI
SCHEMBL15170720 0.85 MGAM (0.34) MGAMGAASIMGAM2PRKCI
SCHEMBL15280118 0.81 CCR1 (0.38)
SCHEMBL29378331 0.80 ENPP3 (0.36) PRKCI
SCHEMBL2794776 0.80
SCHEMBL29660486 0.80
SCHEMBL1002153 0.80
SCHEMBL306515 0.80 ENPP3 (0.36) PRKCI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4626886-A1 JAK INHIBITORS, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS OnQuality Pharmaceuticals China Ltd. (CN) 2025-10-08 EP disclosed
EP-4247812-A1 SUBSTITUTED PYRROLO [2, 3-B] PYRIDINE AND PYRAZOLO [3, 4-B] PYRIDINE DERIVATIVES AS PROTEIN KINASE INHIBITORS Fochon Biosciences, Ltd. (CN) 2023-09-27 EP disclosed
CN-116568686-A Substituted pyrrolo [2,3-b ] pyridine and pyrazolo [3,4-b ] pyridine derivatives as protein kinase inhibitors 重庆复尚源创医药技术有限公司 2023-08-08 CN disclosed
EP-4034108-A1 AZAINDOLE CARBOXAMIDE COMPOUNDS FOR THE TREATMENT OF MYCOBACTERIAL INFECTIONS The Global Alliance for TB Drug Development, Inc. (US) 2022-08-03 EP disclosed
CN-114746090-A Azaindole carboxamide compounds for the treatment of mycobacterial infections 结核病药物开发全球联盟公司 2022-07-12 CN disclosed
WO-2022105746-A1 SUBSTITUTED PYRROLO [2, 3-b] PYRIDINE AND PYRAZOLO [3, 4-b] PYRIDINE DERIVATIVES AS PROTEIN KINASE INHIBITORS FOCHON PHARMACEUTICALS, LTD. (CN) 2022-05-27 WO disclosed