Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 4/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5352170 | 1.00 | TMEM97 (0.38) | TMEM97SIGMAR1ALDH1A1HCRTR2HCRTR1 | |
| SCHEMBL18308953 | 0.80 | TSHR (0.39) | ALDH1A1L3MBTL1TSHRMAPK1TAAR1 | |
| SCHEMBL7991265 | 0.76 | TMEM97 (0.37) | TMEM97SIGMAR1ALDH1A1HCRTR2HCRTR1 | |
| SCHEMBL24489826 | 0.73 | TMEM97 (0.34) | TMEM97SIGMAR1 | |
| SCHEMBL20193587 | 0.73 | TMEM97 (0.34) | TMEM97SIGMAR1 | |
| SCHEMBL22956868 | 0.73 | CA1 (0.36) | TMEM97SIGMAR1 | |
| SCHEMBL20193586 | 0.73 | CA1 (0.36) | TMEM97SIGMAR1 | |
| SCHEMBL23145885 | 0.72 | TMEM97 (0.34) | TMEM97SIGMAR1 | |
| SCHEMBL5606199 | 0.71 | TMEM97 (0.48) | TMEM97SIGMAR1ALDH1A1L3MBTL1TSHR | |
| SCHEMBL2182755 | 0.71 | TMEM97 (0.48) | TMEM97SIGMAR1ALDH1A1L3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007121416-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-10-25 | — | — | WO | disclosed |
| WO-2007121416-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-10-25 | — | — | WO | disclosed |