Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 4/20 | 0.33 |
| ▸ | KLK7 | P49862 | 2/20 | 0.32 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA7 | P43166 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | CASR | P41180 | 1/20 | 0.31 |
| ▸ | TACR1 | P25103 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24489826 | 1.00 | TMEM97 (0.34) | TMEM97SIGMAR1HTTKMT2ACA1 | |
| SCHEMBL22956868 | 0.87 | CA1 (0.36) | TMEM97SIGMAR1HTTKMT2ACA1 | |
| SCHEMBL20193586 | 0.87 | CA1 (0.36) | TMEM97SIGMAR1HTTKMT2ACA1 | |
| SCHEMBL16155184 | 0.81 | SMYD2 (0.39) | HTT | |
| SCHEMBL17511781 | 0.81 | SMYD2 (0.39) | HTT | |
| SCHEMBL16155264 | 0.77 | SMN1; SMN2 (0.31) | — | |
| SCHEMBL19506798 | 0.75 | CA2 (0.32) | CA2 | |
| SCHEMBL20191620 | 0.75 | CA2 (0.32) | CA2 | |
| SCHEMBL24489831 | 0.74 | KMT2A (0.36) | TMEM97SIGMAR1HTTKMT2ACA1 | |
| SCHEMBL5346178 | 0.73 | TMEM97 (0.38) | TMEM97SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9982005-B2 | Macrolides and methods of their preparation and use | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2018-05-29 | — | — | US | disclosed |