SCHEMBL534646

SCHEMBL534646

C=C(C)C(=O)OCCC(F)(F)C(F)(F)CCC(F)(F)C(F)(F)F

nearest known ligand 0.46

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.46
TSHR P16473 3/20 0.44
ALDH1A1 P00352 2/20 0.36
POLB P06746 1/20 0.35
APEX1 P27695 1/20 0.35
HTT P42858 1/20 0.35
TDP1 Q9NUW8 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL534391 1.00 THRB (0.46) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL1415468 0.96 THRB (0.48) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL8519227 0.90 THRB (0.43) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL4449245 0.88 THRB (0.42) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL535041 0.88 THRB (0.42) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL28255973 0.86 TSHR (0.53) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL1536985 0.86 THRB (0.46) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL13024791 0.86 THRB (0.46) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL3843423 0.85 THRB (0.48) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL12199990 0.84 TSHR (0.56) THRBTSHRALDH1A1POLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2276781-B1 ETHYLENE-TETRAFLUOROETHYLENE INTERMEDIATES DU PONT (US) 2012-11-07 EP claimed
US-8212064-B2 Ethylene tetrafluoroethylene intermediates E.I. DU PONT DE NEMOURS AND COMPANY (US) 2012-07-03 US claimed
US-20090287010-A1 Ethylene-tetrafluoroethylene intermediates E.I. DU PONT DE NEMOURS AND COMPANY (US) 2009-11-19 US claimed
US-8318877-B2 Ethylene tetrafluoroethylene (meth)acrylate copolymers E.I. DU PONT DE NEMOURS AND COMPANY (US) 2012-11-27 US disclosed
EP-2276781-B1 ETHYLENE-TETRAFLUOROETHYLENE INTERMEDIATES DU PONT (US) 2012-11-07 EP disclosed
US-8212064-B2 Ethylene tetrafluoroethylene intermediates E.I. DU PONT DE NEMOURS AND COMPANY (US) 2012-07-03 US disclosed
EP-2283051-B1 ETHYLENE TETRAFLUOROETHYLENE (METH)ACRYLATE COPOLYMERS DU PONT (US) 2012-02-08 EP disclosed
EP-2283051-A1 ETHYLENE TETRAFLUOROETHYLENE (METH)ACRYLATE COPOLYMERS E. I. du Pont de Nemours and Company (US) 2011-02-16 EP disclosed
WO-2009143194-A1 ETHYLENE TETRAFLUOROETHYLENE (METH)ACRYLATE COPOLYMERS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2009-11-26 WO disclosed
US-20090291222-A1 Ethylene tetrafluoroethylene (meth)acrylate copolymers E. I. DU PONT DE NEMOURS AND COMPANY (US) 2009-11-26 US disclosed
US-20090287010-A1 Ethylene-tetrafluoroethylene intermediates E.I. DU PONT DE NEMOURS AND COMPANY (US) 2009-11-19 US disclosed