SCHEMBL5347203

SCHEMBL5347203

CC1=Cc2c(-c3ccccc3C(C)C)cccc2C1[Zr](C1C(C)=Cc2c(-c3ccccc3C(C)C)cccc21)[SiH](C)C

nearest known ligand 0.30

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 1/20 0.30
NR1H2 P55055 1/20 0.30
NR1H3 Q13133 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5788443 0.88 FAAH (0.32)
SCHEMBL5889946 0.87 DPP4 (0.30) DPP4NR1H2NR1H3
SCHEMBL5890483 0.84
SCHEMBL5890857 0.84
SCHEMBL2237361 0.83
SCHEMBL5890230 0.83
Hydrochloric Acid SCHEMBL2236809 0.82
SCHEMBL5890682 0.82
SCHEMBL5890141 0.82 TSHR (0.31)
SCHEMBL5360910 0.81 BRD4 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7297747-B2 Polymerization process and polymer composition EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-11-20 US disclosed
US-20050059785-A1 Polymerization process and polymer composition HART JAMES R (US) 2005-03-17 US disclosed
US-20050054520-A1 Metallocenes and catalyst compositions derived therefrom EXXONMOBIL CHEMICAL PATENT INC. 2005-03-10 US disclosed