Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 6/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 5/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | SNCA | P37840 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20488797 | 0.83 | MAOB (0.43) | MAOBCYP1A2CYP2D6TSHRCYP3A4 | |
| SCHEMBL31036773 | 0.82 | PPARG (0.44) | MAOBCYP1A2CYP2D6TSHRCYP3A4 | |
| SCHEMBL4311358 | 0.80 | EPHX1 (0.43) | MAOBCYP1A2CYP2D6TSHRCYP3A4 | |
| SCHEMBL20489214 | 0.80 | MAOB (0.45) | MAOBCYP1A2CYP2D6TSHRCYP3A4 | |
| SCHEMBL7267577 | 0.79 | BLM (0.39) | TAAR1CYP2A6 | |
| SCHEMBL27093013 | 0.79 | SLC6A4 (0.47) | MAOBKDM4ESLC6A2TAAR1SLC6A4 | |
| SCHEMBL14775218 | 0.79 | CYP1A2 (0.46) | MAOBCYP1A2TSHREPHX1PKM | |
| SCHEMBL14775221 | 0.79 | CYP1A2 (0.46) | MAOBCYP1A2TSHREPHX1PKM | |
| SCHEMBL10546279 | 0.79 | MAOB (0.44) | MAOBCYP1A2CYP2D6TSHRCYP3A4 | |
| SCHEMBL20489216 | 0.77 | MAOB (0.42) | MAOBCYP1A2CYP2D6TSHRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108191655-B | Synthetic method and application of American western corn rootworm sex pheromone | 西北农林科技大学 | 2021-05-28 | — | — | CN | claimed |
| CN-118994491-A | Photocurable composition for stereolithography, stereolithography method using the same, polymer assembly formed by the stereolithography method, and device comprising the polymer assembly | 罗杰斯公司 | 2024-11-22 | — | — | CN | disclosed |
| CN-113906066-B | Photocurable composition for stereolithography, stereolithography method using the same, polymer assembly formed by the stereolithography method, and device comprising the polymer assembly | 罗杰斯公司 | 2024-10-01 | — | — | CN | disclosed |
| EP-3704086-B1 | PROCESS FOR PREPARING 4-CHLOROBENZYL PROPARGYL ETHER | BASF SE (DE) | 2024-02-21 | — | — | EP | disclosed |
| WO-2022138791-A1 | EP2 ANTAGONIST | 小野薬品工業株式会社 | 2022-06-30 | — | — | WO | disclosed |
| CN-113906066-A | Photocurable composition for stereolithography, stereolithography method using the same, polymer assembly formed by stereolithography method, and device comprising the polymer assembly | 罗杰斯公司 | 2022-01-07 | — | — | CN | disclosed |
| US-11021413-B2 | Benzylpropargylether as nitrification inhibitors | BASF SE (DE) | 2021-06-01 | — | — | US | disclosed |
| CN-108191655-B | Synthetic method and application of American western corn rootworm sex pheromone | 西北农林科技大学 | 2021-05-28 | — | — | CN | disclosed |
| US-20190276376-A1 | CAPSULES COMPRISING BENZYLPROPARGYLETHERS FOR USE AS NITRIFICATION INHIBITORS | BASF SE (DE) | 2019-09-12 | — | — | US | disclosed |
| US-20190276376-A1 | CAPSULES COMPRISING BENZYLPROPARGYLETHERS FOR USE AS NITRIFICATION INHIBITORS | BASF SE (DE) | 2019-09-12 | — | — | US | disclosed |
| EP-2243777-A1 | Method for manufacturing Pyridyl-substituted pyrazoles | Bayer CropScience AG (DE) | 2010-10-27 | — | — | EP | disclosed |
| WO-2010112178-A1 | METHOD FOR PRODUCING PYRIDYL-SUBSTITUTED PYRAZOLES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2010-10-07 | — | — | WO | disclosed |
| WO-2004072078-A1 | PYRAZOLOTRIAZINE DERIVATIVES, METHODS FOR PRODUCTION AND USES THEREOF | UNIVERSITE LOUIS PASTEUR (FR) | 2004-08-26 | — | — | WO | disclosed |
| EP-0759915-B1 | ASYMMETRIC SYNTHESIS OF CHIRAL SECONDARY ALCOHOLS | CELL THERAPEUTICS INC (US) | 2002-10-16 | — | — | EP | disclosed |
| US-6057328-A | TREATING CONDITIONS RESULTING FROM HYPEROXIA, AND IN PARTICULAR, CONDITIONS RESULTING FROM THERAPEUTIC ADMINISTRATION OF OXYGEN COMPRISING ADMINISTERING XANTHINE COMPOUNDS | CELL THERAPEUTICS, INC. (US) | 2000-05-02 | — | — | US | disclosed |
| WO-1999033468-A9 | METHOD FOR TREATING HYPEROXIA | CELL THERAPEUTICS INC (US) | 1999-09-23 | — | — | WO | disclosed |
| WO-1999033468-A1 | METHOD FOR TREATING HYPEROXIA | CELL THERAPEUTICS, INC. (US) | 1999-07-08 | — | — | WO | disclosed |
| US-5629423-A | Asymmetric synthesis of chiral secondary alcohols | CELL THERAPEUTICS, INC. (US) | 1997-05-13 | — | — | US | disclosed |
| EP-0759915-A1 | ASYMMETRIC SYNTHESIS OF CHIRAL SECONDARY ALCOHOLS | CELL THERAPEUTICS, INC. (US) | 1997-03-05 | — | — | EP | disclosed |
| WO-1995031450-A1 | ASYMMETRIC SYNTHESIS OF CHIRAL SECONDARY ALCOHOLS | CELL THERAPEUTICS, INC. (US) | 1995-11-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11021413-B2 | Benzylpropargylether as nitrification inhibitors | NAT1, PAH, PFAS | MAOB 91/4885CYP1A2 11/4885CYP2D6 331/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.