SCHEMBL5347489

SCHEMBL5347489

COc1ccc(N(c2ccccc2)c2ccc(C=O)cc2)cc1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.66
CYP2A6 P11509 3/20 0.66
TRPA1 O75762 1/20 0.52
TRPM8 Q7Z2W7 5/20 0.51
ALDH3A1 P30838 1/20 0.47
ALDH1A3 P47895 1/20 0.47
CYP2A13 Q16696 1/20 0.46
KDM4E B2RXH2 2/20 0.45
HPGD P15428 1/20 0.45
LMNA P02545 2/20 0.44
MAPT P10636 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
TTR P02766 1/20 0.44
BCHE P06276 1/20 0.44
CYP3A4 P08684 1/20 0.44
NFKB1 P19838 1/20 0.44
NFKB2 Q00653 1/20 0.44
RELA Q04206 1/20 0.44
SERPINE1 P05121 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19275033 1.00 ALDH1A1 (0.66) ALDH1A1CYP2A6TRPA1TRPM8ALDH3A1
SCHEMBL14452808 0.95 ALDH1A1 (0.59) ALDH1A1CYP2A6TRPA1TRPM8ALDH3A1
SCHEMBL19275027 0.95 ALDH1A1 (0.59) ALDH1A1CYP2A6TRPA1TRPM8ALDH3A1
SCHEMBL1128183 0.93 ALDH1A1 (0.76) ALDH1A1CYP2A6TRPA1ALDH3A1ALDH1A3
SCHEMBL7750911 0.93 ALDH1A1 (0.76) ALDH1A1CYP2A6TRPA1ALDH3A1ALDH1A3
SCHEMBL23908231 0.88 ALDH1A1 (0.68) ALDH1A1CYP2A6TRPA1ALDH3A1ALDH1A3
SCHEMBL21738402 0.88 ALDH1A1 (0.68) ALDH1A1CYP2A6TRPA1ALDH3A1ALDH1A3
SCHEMBL17199711 0.88 ALDH1A1 (0.68) ALDH1A1CYP2A6ALDH3A1ALDH1A3CYP2A13
SCHEMBL23918295 0.88 ALDH1A1 (0.68) ALDH1A1CYP2A6TRPA1ALDH3A1ALDH1A3
SCHEMBL10028279 0.88 ALDH1A1 (0.68) ALDH1A1CYP2A6TRPA1ALDH3A1ALDH1A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117624062-A Barbiturates structure-containing compound and preparation method and application thereof 武汉大学 2024-03-01 CN disclosed
CN-115702337-A Functional member and chemical substance sensor provided with same 松下知识产权经营株式会社 2023-02-14 CN disclosed
US-9614172-B2 Curable composition, cured product, and organic electroluminescence element using same NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) 2017-04-04 US disclosed
US-20140326982-A1 CURABLE COMPOSITION, CURED PRODUCT, AND ORGANIC ELECTROLUMINESCENCE ELEMENT USING SAME NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2014-11-06 US disclosed
US-20110200926-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, IMAGE FORMING METHOD, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2011-08-18 US disclosed
US-7524991-B2 Organic electroluminescent devices, aminostyrylnaphthalene compounds and synthesis intermediates thereof, and production processes of the same SONY CORPORATION (JP) 2009-04-28 US disclosed
US-7402344-B2 Organic electroluminescent devices and aminostyrylnaphthalene compounds SONY CORPORATION (JP) 2008-07-22 US disclosed
US-7402344-B2 Organic electroluminescent devices and aminostyrylnaphthalene compounds SONY CORPORATION (JP) 2008-07-22 US disclosed
US-20080051607-A1 ORGANIC ELECTROLUMINESCENT DEVICES, AMINOSTYRLNAPHTHALENE COMPOUNDS AND SYNTHESIS INTERMEDIATES THEREOF, AND PRODUCTION PROCESSES OF THE SAME SONY CORPORATION (JP) 2008-02-28 US disclosed
US-7196225-B2 Bis(aminostyryl) anthracene compound, synthesis intermediate thereof, and process for production thereof SONY CORPORATION (JP) 2007-03-27 US disclosed
EP-0812820-B1 TRIPHENYLAMINE DERIVATIVES, AND CHARGE TRANSPORT MATERIAL AND ELECTROPHOTOGRAPHIC PHOTORECEPTOR PREPARED THEREFROM TAKASAGO PERFUMERY CO LTD (JP) 2001-01-17 EP disclosed
US-6172264-B1 REACTING A TRIPHENYLAMINE WITH A VILSMEIER IN PRESENCE OF ACID CATALYST TAKASAGO INTERNATIONAL CORPORATION (JP) 2001-01-09 US disclosed
US-6069224-A CHARGE TRANSPORTING PROPERTIES, PHOTOSENSITIVITY RICOH COMPANY, LTD. (JP) 2000-05-30 US disclosed
US-6027846-A HIGH PHOTOSENSITIVITY, HIGH DURABILITY RICOH COMPANY, LTD. (JP) 2000-02-22 US disclosed
US-5989765-A CHARGE TRANSPORT MATERIAL IS A TRIPHENYLAMINE DERIVATIVE WHERE ONE OF THE PHENYL GROUPS OF THE TRIPHENYL AMINE HAS A DIPHENYLBUTADIENYL-SUBSTITUENT AND THE OTHER TWO PHENYL GROUPS HAVE A DIPHENYLBUTADIENYL- OR DIPHENYLVINYL-FRAMEWORK TAKASAGO INTERNATIONAL CORPORATION (JP) 1999-11-23 US disclosed
US-5910610-A Triphenylamine derivative, charge-transporting material comprising the same, and electrophotographic photoreceptor TAKASAGO INTERNATIONAL CORPORATION (JP) 1999-06-08 US disclosed
US-5789128-A Electrophotographic photoconductor and aromatic polycarbonate resin for use therein RICOH COMPANY, LTD. (JP) 1998-08-04 US disclosed
EP-0812820-A1 TRIPHENYLAMINE DERIVATIVES, AND CHARGE TRANSPORT MATERIAL AND ELECTROPHOTOGRAPHIC PHOTORECEPTOR PREPARED THEREFROM Takasago International Corporation (JP) 1997-12-17 EP disclosed
EP-0084147-B1 PHENYL HYDRAZONES AND THEIR USE BASF Aktiengesellschaft (DE) 1987-05-27 EP disclosed
EP-0084147-A2 Phenyl hydrazones and their use BASF Aktiengesellschaft (DE) 1983-07-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080051607-A1 ORGANIC ELECTROLUMINESCENT DEVICES, AMINOSTYRLNAPHTHALENE COMPOUNDS AND SYNTHESIS INTERMEDIATES THEREOF, AND PRODUCTION PROCESSES OF THE SAME ASNS, RPS24, L1CAM ALDH1A1 798/4885CYP2A6 1474/4885TRPA1 985/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.