Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | AKT1 | P31749 | 7/20 | 0.42 |
| ▸ | AKT2 | P31751 | 7/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | AHR | P35869 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5321323 | 0.87 | AKT1 (0.50) | KDM4ERAB9AGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL5324372 | 0.85 | AKT1 (0.55) | KDM4ERAB9AGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL5346034 | 0.79 | KDM4E (0.42) | KDM4ERAB9AGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL5353051 | 0.79 | KDM4E (0.42) | KDM4ERAB9AGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL5341559 | 0.79 | DPP4 (0.45) | RAB9ASMN1; SMN2ALDH1A1AKT1AKT2 | |
| SCHEMBL1428401 | 0.78 | AKT2 (0.49) | SMN1; SMN2AKT1AKT2L3MBTL1MEN1 | |
| SCHEMBL5320129 | 0.77 | AKT1 (0.46) | KDM4ERAB9AGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL5343647 | 0.77 | AKT1 (0.48) | KDM4ERAB9AGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL5325683 | 0.77 | AKT1 (0.51) | KDM4ERAB9AGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL5337798 | 0.76 | AKT1 (0.45) | KDM4ERAB9AGAASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007096764-A2 | BICYCLIC HETEROARYL DERIVATIVES AS CANNABINOID RECEPTOR MODULATORS | GLENMARK PHARMACEUTICALS S.A. (US) | 2007-08-30 | — | — | WO | disclosed |
| WO-2007096764-A2 | BICYCLIC HETEROARYL DERIVATIVES AS CANNABINOID RECEPTOR MODULATORS | GLENMARK PHARMACEUTICALS S.A. (US) | 2007-08-30 | — | — | WO | disclosed |