Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 5/20 | 0.51 |
| ▸ | AKT2 | P31751 | 5/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5342012 | 0.91 | AKT1 (0.44) | AKT1AKT2SMN1; SMN2RAB9AGAA | |
| SCHEMBL5344598 | 0.91 | KMT2A (0.53) | AKT1AKT2SMN1; SMN2RAB9AGAA | |
| SCHEMBL5341386 | 0.90 | AKT1 (0.49) | AKT1AKT2SMN1; SMN2RAB9AGAA | |
| SCHEMBL5345880 | 0.89 | PTGS2 (0.55) | AKT1AKT2PTGS2 | |
| SCHEMBL5349048 | 0.89 | AKT1 (0.48) | AKT1AKT2SMN1; SMN2RAB9AGAA | |
| SCHEMBL5322231 | 0.89 | AKT1 (0.48) | AKT1AKT2SMN1; SMN2RAB9AGAA | |
| SCHEMBL5352678 | 0.88 | AKT1 (0.43) | AKT1AKT2SMN1; SMN2RAB9AGAA | |
| SCHEMBL5324372 | 0.88 | AKT1 (0.55) | AKT1AKT2SMN1; SMN2RAB9AGAA | |
| SCHEMBL5349135 | 0.86 | SMN1; SMN2 (0.44) | AKT1AKT2SMN1; SMN2RAB9AGAA | |
| SCHEMBL5338540 | 0.86 | AKT1 (0.46) | AKT1AKT2SMN1; SMN2RAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007096764-A2 | BICYCLIC HETEROARYL DERIVATIVES AS CANNABINOID RECEPTOR MODULATORS | GLENMARK PHARMACEUTICALS S.A. (US) | 2007-08-30 | — | — | WO | claimed |