Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 19/20 | 0.59 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.59 |
| ▸ | VSIR | Q9H7M9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL410633 | 0.96 | S1PR1 (0.61) | S1PR1S1PR3 | |
| SCHEMBL408734 | 0.91 | S1PR1 (0.69) | S1PR1S1PR3 | |
| SCHEMBL18373544 | 0.86 | S1PR1 (0.64) | S1PR1S1PR3 | |
| SCHEMBL534797 | 0.86 | S1PR1 (0.56) | S1PR1S1PR3 | |
| SCHEMBL2806714 | 0.86 | S1PR1 (0.62) | S1PR1S1PR3VSIR | |
| SCHEMBL534900 | 0.85 | S1PR1 (0.61) | S1PR1S1PR3 | |
| SCHEMBL410830 | 0.84 | S1PR1 (0.67) | S1PR1S1PR3 | |
| SCHEMBL320407 | 0.83 | S1PR1 (0.70) | S1PR1S1PR3 | |
| SCHEMBL2809504 | 0.83 | S1PR1 (0.61) | S1PR1S1PR3VSIR | |
| SCHEMBL2805596 | 0.83 | S1PR1 (0.63) | S1PR1S1PR3VSIR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2414341-A2 | OXADIAZOLE DERIVATIVES | Merck Serono SA (CH) | 2012-02-08 | — | — | EP | disclosed |