Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SAT1 | P21673 | 1/20 | 0.44 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.38 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.38 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.38 |
| ▸ | FUCA1 | P04066 | 1/20 | 0.37 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.37 |
| ▸ | MLYCD | O95822 | 2/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | LIPA | P38571 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL5344960 | 0.82 | PAOX (0.45) | FUCA1HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL95570 | 0.82 | — | — | |
| SCHEMBL11420212 | 0.82 | SAT1 (0.60) | SAT1GNAI3GNAO1GNAI1TDP1 | |
| Hydrochloric Acid SCHEMBL6609960 | 0.80 | — | — | |
| SCHEMBL12156420 | 0.79 | PLG (0.48) | SAT1GNAI3GNAO1GNAI1TDP1 | |
| SCHEMBL22870137 | 0.79 | PLG (0.48) | SAT1GNAI3GNAO1GNAI1TDP1 | |
| SCHEMBL20871877 | 0.79 | SAT1 (0.46) | SAT1GNAI3GNAO1GNAI1LIPA | |
| SCHEMBL17355046 | 0.78 | SAT1 (0.61) | SAT1GNAI3GNAO1GNAI1TDP1 | |
| Trifluoroacetic Acid SCHEMBL5348233 | 0.76 | TDP1 (0.42) | DPP8DPP7MLYCDHDAC6TDP1 | |
| Trifluoroacetic Acid SCHEMBL21813736 | 0.75 | CYP2D6 (0.52) | HDAC3HDAC1MLYCDHDAC6TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7214699-B2 | Indazole derivatives as CRF antagonists | ROCHE PALO ALTO LLC (US) | 2007-05-08 | — | — | US | disclosed |