Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.67 |
| ▸ | LMNA | P02545 | 3/20 | 0.67 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.67 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.67 |
| ▸ | RELA | Q04206 | 3/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.65 |
| ▸ | MGLL | Q99685 | 2/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.57 |
| ▸ | ACR | P10323 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11459004 | 1.00 | NPC1 (0.67) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL14131957 | 1.00 | NPC1 (0.67) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL14132233 | 1.00 | NPC1 (0.67) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL9853915 | 1.00 | NPC1 (0.67) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL8535590 | 1.00 | NPC1 (0.67) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL11771472 | 1.00 | NPC1 (0.67) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL11467054 | 0.99 | LMNA (0.67) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL8023132 | 0.99 | LMNA (0.67) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL11763538 | 0.99 | LMNA (0.67) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL10794274 | 0.97 | NPC1 (0.64) | NPC1LMNANFKB1NFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3977768-A | Nematic liquid crystal compositions | DAI NIPPON TORYO KAUBSHIKI KAISHA (JA) | 1976-08-31 | — | — | US | claimed |
| US-7186448-B2 | Composition and method for temporarily fixing solid | JSR CORPORATION (JP) | 2007-03-06 | — | — | US | disclosed |
| US-20060275939-A1 | Composition and method for temporarily fixing solids | JSR CORPORATION (JP) | 2006-12-07 | — | — | US | disclosed |
| EP-1522567-A1 | COMPOSITION AND METHOD FOR TEMPORARILY FIXING SOLID | JSR Corporation (JP) | 2005-04-13 | — | — | EP | disclosed |
| US-20040185187-A1 | Composition and method for temporarily fixing solid | JSR CORPORATION (JP) | 2004-09-23 | — | — | US | disclosed |
| US-4198130-A | Liquid crystal mixtures | HOFFMANN-LA ROCHE INC. (US) | 1980-04-15 | — | — | US | disclosed |
| US-4086002-A | Field effect light shutter employing low temperature nematic liquid crystals | HAFFMANN-LA ROCHE INC. (US) | 1978-04-25 | — | — | US | disclosed |
| US-4037062-A | Liquid crystal electromechanical transducer | FERGASON, JAMES L. | 1977-07-19 | — | — | US | disclosed |
| US-3977768-A | Nematic liquid crystal compositions | DAI NIPPON TORYO KAUBSHIKI KAISHA (JA) | 1976-08-31 | — | — | US | disclosed |
| US-3977768-A | Nematic liquid crystal compositions | DAI NIPPON TORYO KAUBSHIKI KAISHA (JA) | 1976-08-31 | — | — | US | disclosed |
| US-3961843-A | POLY-P-XYLYLENE | DAI NIPPON TORYO KABUSHIKI KAISHA (JA) | 1976-06-08 | — | — | US | disclosed |
| US-3955881-A | Electro-optical device employing nematic liquid crystal | DAI NIPPON TORYO KABUSHIKI KAISHA (JA) | 1976-05-11 | — | — | US | disclosed |