Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | FNTA | P49354 | 2/20 | 0.43 |
| ▸ | FNTB | P49356 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13702339 | 0.83 | SMN1; SMN2 (0.54) | KMT2AGAAHSD17B10SMN1; SMN2MEN1 | |
| SCHEMBL3348765 | 0.81 | CA12 (0.53) | KMT2AGAAHSD17B10CA12CA1 | |
| SCHEMBL5353868 | 0.80 | L3MBTL1 (0.65) | KMT2AGAAHSD17B10SMN1; SMN2MEN1 | |
| SCHEMBL29650963 | 0.80 | HDAC8 (0.59) | KMT2ACA12CA1CA2CA9 | |
| SCHEMBL4820100 | 0.80 | GRM5 (0.58) | KMT2ACA12CA1CA2CA9 | |
| SCHEMBL28527018 | 0.80 | HDAC8 (0.59) | KMT2ACA12CA1CA2CA9 | |
| SCHEMBL31116810 | 0.78 | KDM4E (0.54) | KMT2AGAAHSD17B10CA12CA1 | |
| SCHEMBL27136913 | 0.78 | L3MBTL1 (0.67) | KMT2AGAACA12CA1CA2 | |
| SCHEMBL31607772 | 0.78 | L3MBTL1 (0.67) | KMT2AGAACA12CA1CA2 | |
| SCHEMBL4813469 | 0.78 | HDAC1 (0.57) | KMT2AGAACA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7214715-B2 | Compounds to treat Alzheimer's disease | PHARMACIA & UPJOHN (US) | 2007-05-08 | — | — | US | disclosed |