SCHEMBL5348583

SCHEMBL5348583

Cc1ccc2c(c1)N(c1ccc(N)cn1)CN(C(C)C)N=C2C1CCCCC1

nearest known ligand 0.38

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PTH1R Q03431 15/20 0.38
PIK3CA P42336 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5364319 0.89 PTH1R (0.43) PTH1R
SCHEMBL5352610 0.80 PTH1R (0.54) PTH1RPIK3CA
SCHEMBL5362907 0.72 PTH1R (0.55) PTH1R
SCHEMBL5351792 0.72 PTH1R (0.56) PTH1RPIK3CA
SCHEMBL5322629 0.69 PTH1R (0.63) PTH1R
SCHEMBL5347210 0.66 PTH1R (0.65) PTH1R
SCHEMBL5325975 0.65 PTH1R (0.64) PTH1R
SCHEMBL5326711 0.64 PTH1R (0.57) PTH1R
SCHEMBL5321102 0.64 PTH1R (0.57) PTH1R
SCHEMBL5323133 0.64 PTH1R (0.57) PTH1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007135350-A1 BENZOTRIAZEPINONE DERIVATIVES JAMES BLACK FOUNDATION (GB) 2007-11-29 WO disclosed