Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | CA1 | P00915 | 3/20 | 0.58 |
| ▸ | CA2 | P00918 | 3/20 | 0.58 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.52 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.52 |
| ▸ | CES2 | O00748 | 1/20 | 0.52 |
| ▸ | CES1 | P23141 | 1/20 | 0.52 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.50 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.50 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11985689 | 0.89 | MAPT (0.73) | SMN1; SMN2NPC1RAB9AMAPTCA1 | |
| SCHEMBL11490111 | 0.88 | SMN1; SMN2 (0.56) | SMN1; SMN2NPC1RAB9AMAPTCA1 | |
| SCHEMBL11233009 | 0.87 | TDP1 (0.54) | SMN1; SMN2NPC1RAB9AMAPTCA1 | |
| SCHEMBL6704208 | 0.85 | CA1 (0.62) | SMN1; SMN2NPC1RAB9AMAPTCA1 | |
| SCHEMBL27824110 | 0.85 | SMN1; SMN2 (0.64) | SMN1; SMN2NPC1RAB9AMAPTCA1 | |
| SCHEMBL1988247 | 0.84 | TSHR (0.68) | SMN1; SMN2NPC1RAB9AMAPTCA1 | |
| SCHEMBL13256587 | 0.84 | SMN1; SMN2 (0.62) | SMN1; SMN2NPC1RAB9AMAPTCA1 | |
| SCHEMBL26189841 | 0.84 | RAB9A (0.67) | SMN1; SMN2NPC1RAB9AMAPTCA1 | |
| SCHEMBL20073067 | 0.84 | MAPT (0.62) | SMN1; SMN2NPC1RAB9AMAPTCA1 | |
| SCHEMBL12532605 | 0.84 | NPC1 (0.67) | SMN1; SMN2NPC1RAB9AMAPTCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106810411-B | A kind of method of acyl chlorides and 1,2- dichloroethanes reaction generation ester | 中国科学院大连化学物理研究所 | 2018-09-04 | — | — | CN | disclosed |
| CN-106810411-A | A kind of method of acyl chlorides and 1,2- dichloroethanes reaction generation ester | 中国科学院大连化学物理研究所 | 2017-06-09 | — | — | CN | disclosed |
| US-7276324-B2 | Nitrogen-containing organic compound, resist composition and patterning process | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2007-10-02 | — | — | US | disclosed |
| US-20050106500-A1 | Nitrogen-containing organic compound, resist composition and patterning process | SHIN-ETSU CHEMICAL CO., LTD. | 2005-05-19 | — | — | US | disclosed |
| US-4198416-A | 5-Alkoxy-picolinic esters and anti-hypertensive composition containing 5-alkoxy-picolinic esters | MEIJI SEIKA KAISHA, LTD. (JP) | 1980-04-15 | — | — | US | disclosed |