Known targets — ChEMBL curated mechanism
ABL1BMXBRAFBTKCHRNA4CHRNB2CSNK1EEGFRERBB2F10FLT1FLT3FLT4IGF1RINSRITKJAK3KDRKITOPRM1PARP1PARP2PDGFRBPIK3CDRAF1RETSLC18A2TECTXKdacAdacBdacCftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 2/20 | 0.54 |
| ▸ | CA2 | P00918 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA3 | P07451 | 1/20 | 0.54 |
| ▸ | CA6 | P23280 | 1/20 | 0.54 |
| ▸ | CA5A | P35218 | 1/20 | 0.54 |
| ▸ | CA7 | P43166 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.54 |
| ▸ | NT5E | P21589 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL5512184 | 1.00 | GAA (0.59) | GAALMNAALDH1A1SMN1; SMN2TDP1 | |
| Water SCHEMBL31139173 | 1.00 | GAA (0.59) | GAALMNAALDH1A1SMN1; SMN2TDP1 | |
| Water SCHEMBL4069335 | 1.00 | GAA (0.59) | GAALMNAALDH1A1SMN1; SMN2TDP1 | |
| Water SCHEMBL16460263 | 1.00 | GAA (0.59) | GAALMNAALDH1A1SMN1; SMN2TDP1 | |
| Water SCHEMBL1160667 | 1.00 | GAA (0.59) | GAALMNAALDH1A1SMN1; SMN2TDP1 | |
| Water SCHEMBL214962 | 1.00 | GAA (0.59) | GAALMNAALDH1A1SMN1; SMN2TDP1 | |
| Water SCHEMBL28246842 | 1.00 | GAA (0.59) | GAALMNAALDH1A1SMN1; SMN2TDP1 | |
| Water SCHEMBL6305540 | 0.97 | GAA (0.56) | GAALMNAALDH1A1SMN1; SMN2TDP1 | |
| Methyl Alcohol SCHEMBL8799286 | 0.97 | GAA (0.56) | GAALMNAALDH1A1SMN1; SMN2TDP1 | |
| Water SCHEMBL21836188 | 0.97 | GAA (0.56) | GAALMNAALDH1A1SMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 58079 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117623877-B | Cardanol bisphenol and preparation method and application thereof | CHANGSHU NAISU BIOLOGICAL MATERIAL TECHNOLOGY CO.,LTD. (CN) | 2026-05-26 | — | — | CN | claimed |
| CN-122070479-A | Ultrasonic indicating device and method for monitoring ultrasonic treatment | JP实验室股份有限公司 | 2026-05-19 | — | — | CN | claimed |
| CN-119735282-B | PAM/COF composite material for treating dye wastewater and preparation method thereof | 塔里木大学 | 2026-05-19 | — | — | CN | claimed |
| CN-122037234-A | Temperature-sensitive hydrogel with double-network structure and preparation method and application thereof | 安徽理工大学 | 2026-05-15 | — | — | CN | claimed |
| CN-122055370-A | And cyclic nitrogen-containing compound, crystal form thereof, preparation method and application thereof | 杭州圣域生物医药科技有限公司 | 2026-05-15 | — | — | CN | claimed |
| CN-122010958-A | Synthesis method of natural product Pyrroloazocine indole alkaloid skeleton | 中国医学科学院药物研究所 | 2026-05-12 | — | — | CN | claimed |
| CN-122011886-A | Metal surface anticorrosive paint and preparation method thereof | 深圳市易植医疗科技有限公司 | 2026-05-12 | — | — | CN | claimed |
| EP-4429642-B1 | NIRAPARIB PARTICLES AND USES THEREOF | CRITITECH INC (US) | 2026-04-29 | — | — | EP | claimed |
| EP-4725491-A1 | FGFR4 INHIBITOR COMPOSITION, PREPARATION METHOD THEREFOR AND PHARMACEUTICAL USE THEREOF | Abbisko Therapeutics Co., Ltd. (CN) | 2026-04-15 | — | — | EP | claimed |
| US-20260098048-A1 | IMPROVED PROCESS FOR THE PREPARATION OF RISDIPLAM AND ITS INTERMEDIATES | NATCO PHARMA LTD (IN) | 2026-04-09 | — | — | US | claimed |
| US-4910327-A | Reacting a corresponding aromatic primary amine with a ketoester | AMERICAN CYANAMID COMPANY (US) | 1990-03-20 | — | — | US | claimed |
| EP-0339854-A2 | Synthesis of N-t-alkyl-1,2-diacylhydrazines | ROHM AND HAAS COMPANY (US) | 1989-11-02 | — | — | EP | claimed |
| EP-0305860-A1 | Polyphenylene ether amine salts, flame retardant extrudate of blends thereof and method of making | GENERAL ELECTRIC COMPANY (US) | 1989-03-08 | — | — | EP | claimed |
| US-4782165-A | BUNTE SALT | PFIZER INC. (US) | 1988-11-01 | — | — | US | claimed |
| WO-1986002069-A1 | BIOTIN INTERMEDIATES AND PROCESS THEREFOR | PFIZER INC. (US) | 1986-04-10 | — | — | WO | claimed |
| US-4429112-A | Process of delaying cure of curable resin composition containing cyanate ester compound with benzene sulfonic acid compound | MITSUBISHI GAS CHEMICAL CO., INC. (JP) | 1984-01-31 | — | — | US | claimed |
| US-4179464-A | Preparation of N-(phosphonoacetyl)-L-aspartic acid | SCHULTZ ROBERT J | 1979-12-18 | — | — | US | claimed |
| US-4152198-A | WATERPROOFING | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 1979-05-01 | — | — | US | claimed |
| US-4127568-A | Process for 3β-aminoazetidin-2-ones | ELI LILLY AND COMPANY (US) | 1978-11-28 | — | — | US | claimed |
| US-3994878-A | Syntheses of 24R,25- and 24S,25-dihydroxycholesterol and alkanoyl derivatives thereof | HOFFMANN-LA ROCHE INC. (US) | 1976-11-30 | — | — | US | claimed |