Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 16/20 | 0.47 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5341562 | 0.87 | NR3C1 (0.49) | GRM5NR3C1PGRTDP1KDM4E | |
| SCHEMBL5340807 | 0.80 | NR4A2 (0.52) | GRM5KDM4EALDH1A1MAOB | |
| SCHEMBL5350061 | 0.74 | TDP1 (0.39) | GRM5NR3C1PGRTDP1ALDH1A1 | |
| SCHEMBL5343294 | 0.72 | GRIN1 (0.42) | GRM5NR3C1PGRTDP1MAOB | |
| SCHEMBL15392753 | 0.72 | IDO1 (0.44) | NR3C1PGRTDP1KDM4EALDH1A1 | |
| SCHEMBL11470852 | 0.71 | MAOB (0.46) | KDM4EALDH1A1MAOB | |
| SCHEMBL5343214 | 0.70 | TDP1 (0.47) | NR3C1PGRTDP1KDM4EALDH1A1 | |
| SCHEMBL5342580 | 0.69 | TDP1 (0.47) | NR3C1PGRTDP1KDM4EALDH1A1 | |
| SCHEMBL5343215 | 0.69 | ADORA2A (0.45) | GRM5KDM4EALDH1A1 | |
| SCHEMBL5324596 | 0.68 | TDP1 (0.46) | NR3C1PGRTDP1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007096764-A2 | BICYCLIC HETEROARYL DERIVATIVES AS CANNABINOID RECEPTOR MODULATORS | GLENMARK PHARMACEUTICALS S.A. (US) | 2007-08-30 | — | — | WO | disclosed |