Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | FNTA | P49354 | 5/20 | 0.40 |
| ▸ | FNTB | P49356 | 5/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ICMT | O60725 | 1/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9996000 | 0.71 | TSHR (0.30) | TSHRHSD17B10 | |
| Squalene SCHEMBL1298084 | 0.65 | KMT2A (0.81) | CYP3A4ALDH1A1ALOX15FNTAFNTB | |
| Squalene SCHEMBL1298088 | 0.65 | KMT2A (0.81) | CYP3A4ALDH1A1ALOX15FNTAFNTB | |
| SCHEMBL31652308 | 0.63 | FNTA (0.72) | CYP3A4ALDH1A1ALOX15FNTAFNTB | |
| SCHEMBL5080365 | 0.63 | FNTA (0.72) | CYP3A4ALDH1A1ALOX15FNTAFNTB | |
| SCHEMBL29595985 | 0.63 | FNTA (0.72) | CYP3A4ALDH1A1ALOX15FNTAFNTB | |
| SCHEMBL458220 | 0.63 | FNTA (0.72) | CYP3A4ALDH1A1ALOX15FNTAFNTB | |
| SCHEMBL20435504 | 0.63 | FNTA (0.72) | CYP3A4ALDH1A1ALOX15FNTAFNTB | |
| SCHEMBL1395165 | 0.63 | FNTA (0.72) | CYP3A4ALDH1A1ALOX15FNTAFNTB | |
| SCHEMBL1952603 | 0.63 | FNTA (0.72) | CYP3A4ALDH1A1ALOX15FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE39682-E1 | Farnesyl derivatives and pharmaceutical compositions containing them | RAMOT AT TEL AVIV UNIVERSITY LTD. (IL) | 2007-06-05 | — | — | US | disclosed |
| EP-0729354-B1 | FARNESYL DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | UNIV RAMOT (IL) | 2002-02-06 | — | — | EP | disclosed |
| US-5705528-A | ENZYME INHIBITORS USEFUL IN CANCER THERAPY | RAMOT UNIVERSITY AUTHORITY FOR APPLIED RESEARCH & INDUSTRIAL DEVELOPMENT (IL) | 1998-01-06 | — | — | US | disclosed |