SCHEMBL9996000

SCHEMBL9996000

CCC1C=CC=C(C(=O)O)C1=S

nearest known ligand 0.30

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.30
MAPK1 P28482 1/20 0.30
HSD17B10 Q99714 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8335735 0.74
SCHEMBL5350171 0.71 LMNA (0.41) TSHRHSD17B10
SCHEMBL9575751 0.68 TSHR (0.32) TSHRMAPK1HSD17B10TDP1
SCHEMBL7415459 0.67 ALDH1A1 (0.36)
SCHEMBL10888143 0.64 ALDH1A1 (0.30) HSD17B10
SCHEMBL8637321 0.62 TSHR (0.33) TSHRMAPK1HSD17B10TDP1
SCHEMBL7600368 0.62 TSHR (0.33) TSHRMAPK1HSD17B10TDP1
SCHEMBL11904680 0.60 TSHR (0.36) TSHRMAPK1HSD17B10TDP1
SCHEMBL262994 0.59 PYGM (0.35)
SCHEMBL19750859 0.59 TSHR (0.35) TSHRMAPK1HSD17B10TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2582665-A1 AN IMPROVED PROCESS FOR PREPARATION OF AMISULPRIDE Lupin Limited (IN) 2013-04-24 EP disclosed
US-20130096319-A1 PROCESS FOR PREPARATION OF AMISULPRIDE LUPIN LIMITED (IN) 2013-04-18 US disclosed
WO-2011158084-A1 AN IMPROVED PROCESS FOR PREPARATION OF AMISULPRIDE LUPIN LIMITED (IN) 2011-12-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130096319-A1 PROCESS FOR PREPARATION OF AMISULPRIDE TST, TPMT, MSRB3 TSHR 679/4885MAPK1 2837/4885HSD17B10 1639/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.