SCHEMBL5350176

SCHEMBL5350176

CCCCC[C@H]1CC[C@H]([C@H]2CC[C@H](CCc3ccc(-c4ccc(F)c(F)c4)c(F)c3)CC2)CC1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RARB P10826 3/20 0.39
S1PR3 Q99500 3/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2C8 P10632 1/20 0.34
CYP2D6 P10635 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34
RARA P10276 1/20 0.34
RARG P13631 1/20 0.34
GCGR P47871 1/20 0.32
SLC6A2 P23975 1/20 0.32
SLC6A4 P31645 1/20 0.32
SLC6A3 Q01959 1/20 0.32
FAAH O00519 1/20 0.32
PTGS2 P35354 1/20 0.32
KDM1A O60341 2/20 0.31
AXL P30530 2/20 0.31
TYRO3 Q06418 2/20 0.31
MERTK Q12866 2/20 0.31
S1PR1 P21453 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5350170 1.00 RARB (0.39) RARBS1PR3CYP3A4CYP2C8CYP2D6
SCHEMBL5350165 1.00 RARB (0.39) RARBS1PR3CYP3A4CYP2C8CYP2D6
SCHEMBL5350168 1.00 RARB (0.39) RARBS1PR3CYP3A4CYP2C8CYP2D6
SCHEMBL7770077 0.96 RARB (0.41) RARBS1PR3CYP3A4CYP2C8CYP2D6
SCHEMBL7770075 0.96 RARB (0.41) RARBS1PR3CYP3A4CYP2C8CYP2D6
SCHEMBL4804507 0.92 SLC6A2 (0.34) RARBSLC6A2SLC6A4SLC6A3KDM1A
SCHEMBL4804500 0.92 SLC6A2 (0.34) RARBSLC6A2SLC6A4SLC6A3KDM1A
SCHEMBL4804495 0.92 SLC6A2 (0.34) RARBSLC6A2SLC6A4SLC6A3KDM1A
SCHEMBL4804482 0.92 SLC6A2 (0.34) RARBSLC6A2SLC6A4SLC6A3KDM1A
SCHEMBL4803479 0.91 CYP3A4 (0.39) S1PR3CYP3A4CYP2C8CYP2D6CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7186447-B2 Two plane parallel support plates with frame form cell, with integrated non-linear elements for switching individual picture elements on support plates, and nematic liquid crystal mixture is present in cell, having positive dielectric anisotropy and high resistivity MERCK PATENT GMBH (DE) 2007-03-06 US disclosed
US-20050196551-A1 Matrix liquid crystal display WEBER GEORG (DE) 2005-09-08 US disclosed
US-6905740-B2 The invention relates to a matrix liquid crystal display containing integrated non-linear elements and a liquid crystal mixture which has a particularly high resistivity. MERCK PATENT GMBH (DE) 2005-06-14 US disclosed
US-20030207046-A1 Matrix liquid crystal display MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2003-11-06 US disclosed
US-6562419-B1 Matrix liquid crystal display MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2003-05-13 US disclosed
US-6004479-A FLUOROETHERS FOR LIQUID CRYSTAL DISPLAYS AND DIELECTRICS MERCK KGAA (DE) 1999-12-21 US disclosed
US-5519525-A CONTAINING INTEGRATED NON-LINEAR ELEMENTS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1996-05-21 US disclosed
US-5378395-A Matrix liquid crystal display MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1995-01-03 US disclosed
US-5122295-A Containing liquid crystal mixture with high resistivity MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1992-06-16 US disclosed