Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 3/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | RARA | P10276 | 1/20 | 0.36 |
| ▸ | RARG | P13631 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | GCGR | P47871 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
| ▸ | AXL | P30530 | 2/20 | 0.32 |
| ▸ | TYRO3 | Q06418 | 2/20 | 0.32 |
| ▸ | MERTK | Q12866 | 2/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7770075 | 1.00 | RARB (0.41) | RARBS1PR3CYP3A4CYP2C8CYP2D6 | |
| SCHEMBL5350168 | 0.96 | RARB (0.39) | RARBS1PR3CYP3A4CYP2C8CYP2D6 | |
| SCHEMBL5350176 | 0.96 | RARB (0.39) | RARBS1PR3CYP3A4CYP2C8CYP2D6 | |
| SCHEMBL5350165 | 0.96 | RARB (0.39) | RARBS1PR3CYP3A4CYP2C8CYP2D6 | |
| SCHEMBL5350170 | 0.96 | RARB (0.39) | RARBS1PR3CYP3A4CYP2C8CYP2D6 | |
| SCHEMBL8771425 | 0.91 | SLC6A2 (0.36) | RARBSLC6A2SLC6A4SLC6A3GPR84 | |
| SCHEMBL8771431 | 0.91 | SLC6A2 (0.36) | RARBSLC6A2SLC6A4SLC6A3GPR84 | |
| SCHEMBL7510169 | 0.90 | CYP3A4 (0.41) | S1PR3CYP3A4CYP2C8CYP2D6CYP2C9 | |
| SCHEMBL7754624 | 0.90 | CYP3A4 (0.41) | S1PR3CYP3A4CYP2C8CYP2D6CYP2C9 | |
| SCHEMBL8902637 | 0.89 | RARB (0.44) | RARBS1PR3CYP3A4CYP2C8CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0700983-B1 | Electrooptical liquid crystal system | MERCK PATENT GMBH (DE) | 2001-07-11 | — | — | EP | disclosed |
| EP-0799878-A1 | Liquid crystal compositions and liquid crystal display elements containing same | Shin-Etsu Chemical Co., Ltd. (JP) | 1997-10-08 | — | — | EP | disclosed |
| EP-0511487-B1 | Electro-optical liquid crystal system | MERCK PATENT GMBH (DE) | 1996-05-29 | — | — | EP | disclosed |
| EP-0700983-A2 | Electrooptical liquid crystal system | MERCK PATENT GmbH (DE) | 1996-03-13 | — | — | EP | disclosed |
| EP-0511487-A1 | Electro-optical liquid crystal system | MERCK PATENT GmbH (DE) | 1992-11-04 | — | — | EP | disclosed |