SCHEMBL535044

SCHEMBL535044

Ic1cnc(-c2ccccc2)[nH]1

nearest known ligand 0.61

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SCN2A Q99250 7/20 0.61
NPY5R Q15761 3/20 0.61
PIN1 Q13526 1/20 0.53
HPGDS O60760 8/20 0.52
RECQL P46063 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17810406 0.80 NPY5R (0.62) NPY5RHPGDS
SCHEMBL27908765 0.79 NISCH (0.46) SCN2ANPY5RHPGDS
SCHEMBL7380282 0.76 SCN2A (0.63) SCN2ANPY5RPIN1HPGDSRECQL
SCHEMBL2174976 0.76 SCN2A (1.00) SCN2ANPY5RHPGDS
SCHEMBL5371995 0.74 SCN2A (0.61) SCN2ANPY5RPIN1HPGDSRECQL
SCHEMBL11013182 0.74 SCN2A (0.61) SCN2ANPY5RPIN1HPGDSRECQL
SCHEMBL17283469 0.74 SCN2A (0.96) SCN2ANPY5RHPGDS
SCHEMBL16090411 0.74 SCN2A (0.61) SCN2ANPY5RPIN1HPGDSRECQL
SCHEMBL236656 0.74 SCN2A (0.61) SCN2ANPY5RPIN1HPGDSRECQL
SCHEMBL2449258 0.74 SCN2A (0.61) SCN2ANPY5RPIN1HPGDSRECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109126875-B Carbon 60-bidentate nitrogen heterocyclic carbene palladium (0) compound and preparation method and application thereof 洛阳师范学院 2021-03-16 CN disclosed
EP-3227295-B1 6,7-DIHYDROPYRAZOLO[1,5- ]PYRAZIN-4(5H)-ONE COMPOUNDS AND THEIR USE AS NEGATIVE ALLOSTERIC MODULATORS OF MGLU2 RECEPTORS JANSSEN PHARMACEUTICA NV (BE) 2019-02-20 EP disclosed
WO-2016087487-A1 6,7-DIHYDROPYRAZOLO[1,5-α]PYRAZIN-4(5H)-ONE COMPOUNDS AND THEIR USE AS NEGATIVE ALLOSTERIC MODULATORS OF MGLUR2 RECEPTORS JANSSEN PHARMACEUTICA NV (BE) 2016-06-09 WO disclosed
CN-101679191-B Di(hetero)arylcyclohexane derivatives, their preparation, their use and pharmaceutical compositions comprising them SANOFI AVENTIS SPA 2014-03-12 CN disclosed
EP-1952918-B1 METHOD FOR PRODUCING METAL PARTICLE DISPERSION, CONDUCTIVE INK USING METAL PARTICLE DISPERSION PRODUCED BY SUCH METHOD, AND CONDUCTIVE COATING FILM TOYO INK MFG CO (JP) 2013-05-22 EP disclosed
US-8440110-B2 Method for producing metal particle dispersion, conductive ink using metal particle dispersion produced by such method, and conductive coating film TOYO INK MFG CO., LTD. (JP) 2013-05-14 US disclosed
CN-101287566-B Method for producing metal microparticle dispersion, conductive ink using metal microparticle dispersion produced by the method, and conductive coating film TOYO INK MFG CO 2012-05-23 CN disclosed
EP-1990377-B1 COLORED METALLIC PIGMENT, PROCESS FOR PRODUCING THE SAME, AND COATING COMPOSITION AND COSMETIC PREPARATION CONTAINING SAID COLORED METALLIC PIGMENT TOYO ALUMINIUM KK (JP) 2012-02-08 EP disclosed
CN-101384674-B Colored metallic pigment, process for producing the same, and coating composition and cosmetic preparation comprising said colored metallic pigment TOYO ALUMINIUM KABUSHIKI KAISHA (JP) 2011-12-28 CN disclosed
US-7998266-B2 Colored metallic pigment, process for producing the same, and coating composition and cosmetic preparation containing said colored metallic pigment TOYO ALUMINIUM KABUSHIKI KAISHA (JP) 2011-08-16 US disclosed
US-20110175040-A1 METHOD FOR PRODUCING METAL PARTICLE DISPRESION, CONDUCTIVE INK USING METAL PARTICLE DISPERSION PRODUCED BY SUCH METHOD, AND CONDUCTIVE COATING FILM TOYO INK MFG CO., LTD. (JP) 2011-07-21 US disclosed
US-7981327-B2 Method for producing metal particle dispersion, conductive ink using metal particle dispersion produced by such method, and conductive coating film TOYO INK MFG. CO. LTD. (JP) 2011-07-19 US disclosed
CN-101878219-A Imidazothiadiazoles for use as protein kinase inhibitors CT NAC DE INVESTIGACIONES ONCO 2010-11-03 CN disclosed
CN-101679191-A Di(hetero)arylcyclohexane derivatives, their preparation, their use and pharmaceutical compositions comprising them SANOFI AVENTIS 2010-03-24 CN disclosed
US-20090258202-A1 Method for Producing Metal Particle Dispersion, Conductive Ink Using Metal Particle Dispersion Produced by Such Method, and Conductive Coating Film GVP GESELLSCHAFT ZUR VERMARKTUNG DER PORENBRENNERTECHNIK MBH (DE) 2009-10-15 US disclosed
CN-101384674-A Colored metallic pigment, process for producing the same, and coating composition and cosmetic preparation comprising said colored metallic pigment TOYO ALUMINIUM KK (JP) 2009-03-11 CN disclosed
US-20090017082-A1 COLORED METALLIC PIGMENT, PROCESS FOR PRODUCING THE SAME, AND COATING COMPOSITION AND COSMETIC PREPARATION CONTAINING SAID COLORED METALLIC PIGMENT TOYO ALUMINIUM KABUSHIKI KAISHA (JP) 2009-01-15 US disclosed
EP-1990377-A1 COLORED METALLIC PIGMENT, PROCESS FOR PRODUCING THE SAME, AND COATING COMPOSITION AND COSMETIC PREPARATION COMPRISING SAID COLORED METALLIC PIGMENT TOYO ALUMINIUM KABUSHIKI KAISHA (JP) 2008-11-12 EP disclosed
CN-101287566-A Method for producing metal microparticle dispersion, conductive ink using metal microparticle dispersion produced by the method, and conductive coating film TOYO INK MFG CO (JP) 2008-10-15 CN disclosed
EP-1952918-A1 METHOD FOR PRODUCING METAL PARTICLE DISPERSION, CONDUCTIVE INK USING METAL PARTICLE DISPERSION PRODUCED BY SUCH METHOD, AND CONDUCTIVE COATING FILM Toyo Ink Mfg. Co., Ltd (JP) 2008-08-06 EP disclosed