SCHEMBL2174976

SCHEMBL2174976

c1ccc(-c2cnc(-c3ccccc3)[nH]2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SCN2A Q99250 7/20 1.00
NPY5R Q15761 4/20 1.00
HPGDS O60760 8/20 0.75
MASP2 O00187 1/20 0.61
SMPD3 Q9NY59 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17283469 0.98 SCN2A (0.96) SCN2ANPY5RHPGDSMASP2
SCHEMBL85047 0.90 NPY5R (1.00) SCN2ANPY5RHPGDS
SCHEMBL17269682 0.90 NPY5R (1.00) SCN2ANPY5RHPGDS
SCHEMBL27815623 0.89 SCN2A (0.79) SCN2ANPY5RHPGDS
SCHEMBL27843962 0.89 SCN2A (0.79) SCN2ANPY5RHPGDSSMPD3
SCHEMBL27817123 0.89 SCN2A (0.79) SCN2ANPY5RHPGDSMASP2
SCHEMBL2313123 0.86 HPGDS (1.00) SCN2ANPY5RHPGDS
SCHEMBL2317578 0.86 HPGDS (1.00) SCN2ANPY5RHPGDS
SCHEMBL9783786 0.86 SCN2A (0.73) SCN2ANPY5RHPGDSSMPD3
SCHEMBL9783778 0.86 SCN2A (0.73) SCN2ANPY5RHPGDSSMPD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119661817-A Synthetic method of liquid crystal polyarylester and application of high-boiling-point imidazole catalyst in synthesis of liquid crystal polyarylester 浙江聚领新材料有限公司 2025-03-21 CN claimed
EP-0397529-B1 Photohardenable electrostatic element with improved environmental latitude DU PONT (US) 1994-11-23 EP claimed
CN-119661817-A Synthetic method of liquid crystal polyarylester and application of high-boiling-point imidazole catalyst in synthesis of liquid crystal polyarylester 浙江聚领新材料有限公司 2025-03-21 CN disclosed
US-20230348396-A1 HYDROXYBENZAMIDE DERIVATIVES AND METHODS OF USE IN TREATING DIABETES THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA (US) 2023-11-02 US disclosed
US-20230348396-A1 HYDROXYBENZAMIDE DERIVATIVES AND METHODS OF USE IN TREATING DIABETES THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA (US) 2023-11-02 US disclosed
WO-2023073115-A1 PROTEIN AGGREGATION INHIBITING COMPOUNDS FOR PLANT DISEASE CONTROL MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2023-05-04 WO disclosed
EP-3573957-B1 COMPOSITIONS AND METHODS FOR BLOCKING SODIUM CHANNELS RIVARA MIRKO (IT) 2023-04-26 EP disclosed
CN-115524926-A Method for manufacturing semiconductor device 台湾积体电路制造股份有限公司 2022-12-27 CN disclosed
US-11090289-B2 Compositions and methods for blocking sodium channels UNIVERSITY OF VIRGINIA PATENT FOUNDATION 2021-08-17 US disclosed
CN-108473516-B Water-soluble derivatives of 3, 5-diphenyl-diazole compounds 马克斯·普朗克科学促进协会 2021-06-18 CN disclosed
EP-3390412-B1 WATER-SOLUBLE DERIVATIVES OF 3,5-DIPHENYL-DIAZOLE COMPOUNDS MAX PLANCK GESELLSCHAFT (DE) 2021-04-14 EP disclosed
US-5418094-A Color filter FUJI PHOTO FILM CO., LTD. (JP) 1995-05-23 US disclosed
US-5409800-A Temporary substrate having alkali soluble thermoplastic resin layer, intermediate layer, and photosensitive resin layer, interlaminar adhesion being least at interface between thermoplastic layer and the temporary substrate FUJI PHOTO FILM CO., LTD. (JP) 1995-04-25 US disclosed
US-5294516-A Peel-off support, alkali-soluble thermoplastic resin layer, a water- or alkali-soluble or -dispersible interlayer of low oxygen permeability and light sensitive resin layer FUJI PHOTO FILM CO., LTD. (JP) 1994-03-15 US disclosed
US-5176981-A Color proofs FUJI PHOTO FILM CO., LTD. (JP) 1993-01-05 US disclosed
US-4164480-A POLYMER STABILIZERS EASTMAN KODAK COMPANY (US) 1979-08-14 US disclosed
US-4105631-A MULTICHROMOPHORIC ULTRAVIOLET STABILIZERS AND THEIR USE IN ORGANIC COMPOSITIONS EASTMAN KODAK COMPANY (US) 1978-08-08 US disclosed
US-4043973-A PIGMENTS, COLORANTS, FILLERS, REINFORCING AGENTS EASTMAN KODAK COMPANY (US) 1977-08-23 US disclosed
US-3939115-A OXADIAZOLES EASTMAN KODAK COMPANY (US) 1976-02-17 US disclosed
US-3936419-A Multichromophoric ultraviolet stabilizers and their use in organic compositions EASTMAN KODAK COMPANY (US) 1976-02-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11090289-B2 Compositions and methods for blocking sodium channels SCN3A, SCN1B, SCN2B SCN2A 7/4885NPY5R 573/4885HPGDS 2704/4885
US-20230348396-A1 HYDROXYBENZAMIDE DERIVATIVES AND METHODS OF USE IN TREATING DIABETES HSPA5, IAPP, TFEB SCN2A 1838/4885NPY5R 1202/4885HPGDS 600/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.