Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | MAOA | P21397 | 17/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5359994 | 0.87 | CYP3A4 (0.59) | CYP3A4CYP2D6MAOACYP2C9 | |
| SCHEMBL4896038 | 0.86 | MAOA (0.74) | CYP3A4CYP2D6MAOACYP2C9 | |
| SCHEMBL4897434 | 0.81 | MAOA (0.75) | CYP3A4CYP2D6MAOACYP2C9 | |
| SCHEMBL3328495 | 0.79 | CYP3A4 (0.79) | CYP3A4CYP2D6MAOACYP2C9 | |
| SCHEMBL3328501 | 0.79 | CYP3A4 (0.79) | CYP3A4CYP2D6MAOACYP2C9 | |
| SCHEMBL3328493 | 0.79 | CYP3A4 (0.79) | CYP3A4CYP2D6MAOACYP2C9 | |
| SCHEMBL4887794 | 0.78 | MAOA (0.72) | CYP3A4CYP2D6MAOACYP2C9 | |
| SCHEMBL4895217 | 0.77 | MAOA (0.81) | CYP3A4CYP2D6MAOACYP2C9 | |
| SCHEMBL4895902 | 0.75 | MAOA (0.74) | CYP3A4CYP2D6MAOACYP2C9 | |
| SCHEMBL4901157 | 0.75 | MAOA (0.80) | CYP3A4CYP2D6MAOACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1753754-A1 | 3- '4- {6-SUBSTITUTED ALKANOYL) PYRIDIN-3-YL} -3-PHENYL! -5- (1H-1, 2, 3-TRIAZOL-1-YLMETHYL) -1, 3-OXAZOLIDIN-2-ONES AS ANTIBACTERIAL AGENTS | AstraZeneca AB (SE) | 2007-02-21 | — | — | EP | disclosed |
| WO-2005116022-A1 | 3- `4- {6-SUBSTITUTED ALKANOYL) PYRIDIN-3-YL} -3-PHENYL! -5- (1H-1, 2, 3-TRIAZOL-1-YLMETHYL) -1, 3-OXAZOLIDIN-2-ONES AS ANTIBACTERIAL AGENTS | ASTRAZENECA AB (SE) | 2005-12-08 | — | — | WO | disclosed |