Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 2/20 | 0.45 |
| ▸ | BRD4 | O60885 | 3/20 | 0.43 |
| ▸ | HCAR3 | P49019 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | FGB | P02675 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5356781 | 0.91 | ADORA1 (0.45) | ADORA1SMN1; SMN2LMNAHIF1ACSNK2A1 | |
| SCHEMBL5358536 | 0.89 | CRBN (0.44) | ADORA1BRD4 | |
| SCHEMBL5355200 | 0.85 | ADORA1 (0.38) | ADORA1BRD4SMN1; SMN2LMNAHIF1A | |
| SCHEMBL5355195 | 0.85 | BRD4 (0.43) | ADORA1BRD4HPGDLMNAKMT2A | |
| SCHEMBL5350993 | 0.81 | TNKS (0.42) | ADORA1BRD4LMNA | |
| SCHEMBL5359257 | 0.81 | ADORA1 (0.41) | ADORA1BRD4SMN1; SMN2HPGDHSD17B10 | |
| SCHEMBL5368068 | 0.80 | ADORA1 (0.40) | ADORA1SMN1; SMN2LMNAHIF1A | |
| SCHEMBL5359370 | 0.78 | ACSS2 (0.45) | ADORA1BRD4HPGDHSD17B10MEN1 | |
| SCHEMBL5358047 | 0.77 | BRD4 (0.48) | BRD4HCAR3SMN1; SMN2HPGDHCAR2 | |
| SCHEMBL5355821 | 0.77 | ADORA1 (0.46) | ADORA1SMN1; SMN2LMNAHIF1AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7202245-B2 | Substituted 4-amino[1,2,4]triazolo[4,3-a] quinoxalines | PFIZER INC. (US) | 2007-04-10 | — | — | US | disclosed |
| US-20040192698-A1 | Substituted 4-amino[1,2,4]triazolo[4,3-a] quinoxalines | PFIZER INC. | 2004-09-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040192698-A1 | Substituted 4-amino[1,2,4]triazolo[4,3-a] quinoxalines | CYP4B1, CYP3A4, CYP1B1 | ADORA1 12/4885BRD4 784/4885HCAR3 482/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.